Protein Alignment SLC1A3 and slc1a3a

DIOPT Version :10

• Sequence 1: NP_001425387.1
• Gene: SLC1A3 / 6507
• HGNCID: 10941
• Length: 589
• Species: Homo sapiens
• Sequence 2: NP_997805.1
• Gene: slc1a3a / 323439
• ZFINID: ZDB-GENE-030131-2159
• Length: 537
• Species: Danio rerio
• Alignment Length: 591
• Identity: 412/591 - (69%)
• Similarity: 477/591 - (80%)
• Gaps: 56/591 - (9%)

Human     1 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILG 65
            ||:||||......|:::.:.|:.:|:|.||..||||:..|||.:..|||||:|||.|||||.|||
Zfish     1 MTQSNGETRLQRSRVQQLRDGLTERSLRAKNTVQNISSNDVKGFFMRNAFVILTVAAVIVGIILG 65

Human    66 FTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTT 130
            |.||||:|||||||||||||||||||||||||||::|||:||||||||:||||||:||||||.||
Zfish    66 FGLRPYKMSYREVKYFSFPGELLMRMLQMLVLPLLVSSLITGMAALDSRASGKMGVRAVVYYTTT 130

Human   131 TIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYE 195
            |||||.|||::|:|||||||:|:...:..||.:|:.|||||||||||||||||:||.:||||.|.
Zfish   131 TIIAVFIGIVMVLIIHPGKGSKDEFTKHEKIEQVSPADAFLDLIRNMFPPNLVQACTQQFKTQYG 195

Human   196 KRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNM 260
            ||...|.:..|:|:..  :||.::.::     .||::||.|:|||:|||||||||||||.:||||
Zfish   196 KRVVTVKVLVNDTVFS--LNNGTQELK-----REEVIPVLGTVNGINALGLVVFSMCFGLIIGNM 253

Human   261 KEQGQALREFFDSLNEAIMRLVAVIMWSKRKTLCPRAILSEGKARFCKNQGKFIFTKEKKEVHSF 325
            |||||.||:|||.||||||||||:|||
Zfish   254 KEQGQPLRDFFDCLNEAIMRLVAIIMW-------------------------------------- 280

Human   326 CKKRSPQFLYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRK 390
                     |||:||:||||||||||:|:..:||||.|||:|||:||||||||||||||||||||
Zfish   281 ---------YAPLGIMFLIAGKIVEMDDLSEMGGQLGMYTITVIIGLLIHAVIVLPLLYFLVTRK 336

Human   391 NPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEAL 455
            ||:|||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   337 NPFVFIAGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEAL 401

Human   456 AAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDW 520
            |||||||||:.|:|||:|:||||||||||||||||||||||||||||||||||||||||||||||
Zfish   402 AAIFIAQVNDMEMNFGEILTISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDW 466

Human   521 FLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETE--KPI 583
            |||||||||||||||:|||||||||||||::.|.|:||||:||||.||.||||:|::|::  |..
Zfish   467 FLDRLRTTTNVLGDSIGAGIVEHLSRHELRSIDAEIGNSVLEENETKKSYQLISQESESDNAKIP 531

Human   584 DSETKM 589
            |||:||
Zfish   532 DSESKM 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC1A3	NP_001425387.1	None
slc1a3a	NP_997805.1	GltP	46..507	CDD:440912	374/514 (73%)