Protein Alignment CDK15 and cka1

DIOPT Version :10

• Sequence 1: NP_001353315.1
• Gene: CDK15 / 65061
• HGNCID: 14434
• Length: 435
• Species: Homo sapiens
• Sequence 2: NP_593642.1
• Gene: cka1 / 2541972
• PomBaseID: SPAC23C11.11
• Length: 332
• Species: Schizosaccharomyces pombe
• Alignment Length: 318
• Identity: 93/318 - (29%)
• Similarity: 161/318 - (50%)
• Gaps: 47/318 - (14%)

Human    97 FGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAI-REASLLKGLKHA- 159
            ||...:|..:.|:|.|.|:.|::|::.:|.....:||:     :.|.:..| ||..:|:.|...
pombe    37 FGYQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVL-----KPVKYKKIKREIKILQNLAGGP 96

Human   160 NIVLLHDIIHTKETLT--FVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLH 222
            ||:.|.||:...|:.|  .:||::  |...:.:.:| .|..:::|.:.::||:.|.:.|.:.::|
pombe    97 NIISLLDIVRDPESKTPSLIFEFV--DNIDFRTLYP-TLSDYDIRYYSYELLKALDFCHSRGIMH 158

Human   223 RDLKPQNLLISH-LGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGA 286
            ||:||.|::|.| ..:|:|.|:|||.... ....|:..|.:.:::.|:.|:...||...||||..
pombe   159 RDVKPHNVMIDHKKRKLRLIDWGLAEFYH-AGMEYNVRVASRYFKGPELLVDFREYDYSLDIWSF 222

Human   287 GCIFIEM-FQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVV 350
            |.:|..: |:....|.|..| .:||.||.:|||  |::.:..|.|        :.:...|...
pombe   223 GVMFAALIFKKDTFFRGRDN-YDQLVKIAKVLG--TDELFAYVQK--------YQIVLDRQYD-- 274

Human   351 WNRLGRVP------------------EAEDLASQMLKGFPRDRVSAQEALVHDYFSAL 390
             |.||:.|                  ||.||.:::|:...::|::.|||:.|.||..|
pombe   275 -NILGQYPKRDWYSFVNRDNRSLANDEAIDLLNRLLRYDHQERLTCQEAMAHPYFQVL 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK15	NP_001353315.1	STKc_PFTAIRE2	102..387	CDD:270852	88/308 (29%)
cka1	NP_593642.1	STKc_CK2_alpha	24..329	CDD:271034	91/314 (29%)