Protein Alignment CDK15 and pmk1

DIOPT Version :10

• Sequence 1: NP_001353315.1
• Gene: CDK15 / 65061
• HGNCID: 14434
• Length: 435
• Species: Homo sapiens
• Sequence 2: NP_595289.1
• Gene: pmk1 / 2539920
• PomBaseID: SPBC119.08
• Length: 422
• Species: Schizosaccharomyces pombe
• Alignment Length: 328
• Identity: 107/328 - (32%)
• Similarity: 165/328 - (50%)
• Gaps: 44/328 - (13%)

Human   106 LEKLGEGSYATV--YKGISRINGQLVAL-KVISMNAEEGVPFTAIREASLLKGLK-HANIVLLHD 166
            :::||:|:|..|  .:.::..:.:.||: |:.::.::..:...|:||..||...: |.||..::|
pombe    24 VKELGQGAYGIVCAARNVASKDQEAVAIKKITNVFSKSILTKRALREIKLLIHFRNHRNITCIYD 88

Human   167 I-IHTKETLTFVF---EYMHTDL-AQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLK 226
            : |........|:   |.|..|| |...|..|  |...:.:.|::|:|.||.|||..:|:|||||
pombe    89 LDIINPYNFNEVYIYEELMEADLNAIIKSGQP--LTDAHFQSFIYQILCGLKYIHSANVIHRDLK 151

Human   227 PQNLLISHLGELKLADFGLARAKS-IPSQT--YSSE-VVTLWYRPPDALLGATEYSSELDIWGAG 287
            |.|||::...|||:.||||||..| .|.:.  :.:| |.|.|||.|:.:|..:.|...:|:|..|
pombe   152 PGNLLVNADCELKICDFGLARGCSENPEENPGFMTEYVATRWYRAPEIMLSFSSYHKGIDVWSVG 216

Human   288 CIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVS---------KLPNYNPEWFPLPT 343
            ||..|:..|.|||.| .:.:.||..|...||.|.|:|...:|         .||...|..|....
pombe   217 CILAELLGGTPLFKG-KDFVHQLNLILHQLGTPDEETLSHISSSRAQEYVRSLPKQRPIPFETNF 280

Human   344 PRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEE----SLF 404
            |::          .|.|.||.:::|...|..|:|..:||.|.|.:     ::..|.:|    |:|
pombe   281 PKA----------NPLALDLLAKLLAFDPNRRISVDDALEHPYLA-----VWHDPSDEPVCDSVF 330

Human   405 TVS 407
            ..|
pombe   331 DFS 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK15	NP_001353315.1	STKc_PFTAIRE2	102..387	CDD:270852	101/302 (33%)
pmk1	NP_595289.1	STKc_MPK1	20..351	CDD:173750	107/328 (33%)