DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MRPS15 and Mrps15

DIOPT Version :9

Sequence 1:	NP_112570.2	Gene:	MRPS15 / 64960	HGNCID:	14504	Length:	257	Species:	Homo sapiens
Sequence 2:	NP_001007654.1	Gene:	Mrps15 / 298517	RGDID:	1359675	Length:	257	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	164/258 - (63%)
Similarity:	203/258 - (78%)	Gaps:	3/258 - (1%)

- Green bases have known domain annotations that are detailed below.

Human     1 MLRVAWRTLSLIRTRAVTQVLVPGLPGGGSAKFPFNQWGLQPRSLLLQAARGYVVRKPAQSRLDD 65
            |||.|||.||.:|.:||||..||.|....||..|..:.|||..| ||.|||.|.|:||.|::.||
  Rat     1 MLRAAWRALSSVRVQAVTQAPVPALRARSSASLPSARCGLQTPS-LLNAARAYAVQKPVQAKQDD 64

Human    66 DPPPSTLLKDYQN-VPGIEKVDDVVKRLLSLEMANKKEMLKIKQEQFMKKIVANPEDTRSLEARI 129
            :|..||.:|:|:| :|.:|||||||||:||||||::||.||||:||.|.||..||||.|:|||||
  Rat    65 EPASSTFIKEYKNIIPNMEKVDDVVKRILSLEMASRKEKLKIKREQLMNKIAENPEDYRTLEARI 129

Human   130 IALSVKIRSYEEHLEKHRKDKAHKRYLLMSIDQRKKMLKNLRNTNYDVFEKICWGLGIEYTFPPL 194
            :||:||||:||||::||||||.|||:||||||||||.|:.||.||||||||.|..||:||..|||
  Rat   130 VALTVKIRNYEEHMQKHRKDKVHKRHLLMSIDQRKKFLRLLRQTNYDVFEKTCKELGVEYALPPL 194

Human   195 YYRRAHRRFVTKKALCIRVFQETQKLKKRRRALKAAAAAQKQAKR-RNPDSPAKAIPKTLKDS 256
            :::|.||||:.||||||:||||.|||||:|.||||||||.|:.|| |.|::|:.|:|:..|::
  Rat   195 HFQRVHRRFLAKKALCIQVFQEVQKLKKQRMALKAAAAAAKKEKRERVPENPSNALPEKTKEN 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MRPS15	NP_112570.2	Ribosomal_S15	112..187	CDD:395247	55/74 (74%)
MRPS15	NP_112570.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	225..257		17/33 (52%)
Mrps15	NP_001007654.1	Ribosomal_S15	112..186	CDD:395247	54/73 (74%)
Mrps15	NP_001007654.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	228..257		15/28 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83679096
Domainoid	1	1.000	123	1.000	Domainoid score	I37761
eggNOG	1	0.900	-	-		E1_COG0184
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32636
Inparanoid	1	1.050	321	1.000	Inparanoid score	I14373
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG36226
OrthoDB	1	1.010	-	-		D1539741at2759
OrthoFinder	1	1.000	-	-		FOG0003129
OrthoInspector	1	1.000	-	-		oto134690
orthoMCL	1	0.900	-	-		OOG6_101240
Panther	1	1.100	-	-	LDO	PTHR46685
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X8993
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	18.270