DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment BMP1 and CG9372

DIOPT Version :9

Sequence 1:NP_006120.1 Gene:BMP1 / 649 HGNCID:1067 Length:986 Species:Homo sapiens
Sequence 2:NP_649132.1 Gene:CG9372 / 40137 FlyBaseID:FBgn0036891 Length:408 Species:Drosophila melanogaster


Alignment Length:232 Identity:41/232 - (17%)
Similarity:64/232 - (27%) Gaps:100/232 - (43%)


- Green bases have known domain annotations that are detailed below.


Human   459 KVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRD---------GHSESSTLIGRYCGYEK 514
            |..:|.:.:..|:....|...       :.:.|:|::.|         |.||:..       || 
  Fly     2 KAFLWALVILLGYIPQSTIAK-------TVSTDFLDLLDFSDNDEFQWGESENQV-------YE- 51

Human   515 PDDIKSTSSRLWLKFVSDGSINKAGFAVNFF---KEVDECSRPNRGGCEQRCLNTLGSYKCSCDP 576
                ..|.....:.|:|...:||.....:..   |:...||.|            ||        
  Fly    52 ----NRTGENRVVSFLSQHRLNKRQAPTSQLLENKDYGACSTP------------LG-------- 92

Human   577 GYELAPDKRRCE--AACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETE 639
                  :..||.  ..|                  ..|..||.:|:||:        |....|..
  Fly    93 ------ESGRCRHIIYC------------------RMPELKNDVWRLVS--------QLCIIEKS 125

Human   640 GNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676
            ...:|           ..|.....:|    .|:|:||
  Fly   126 SIGIC-----------CTDQSTSNRF----SPQVVTS 147

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BMP1NP_006120.1 ZnMc_BMP1_TLD 121..320 CDD:239808
Astacin 128..321 CDD:279708
CUB 322..431 CDD:278839
CUB 435..544 CDD:278839 17/93 (18%)
FXa_inhibition 555..587 CDD:291342 2/31 (6%)
CUB 591..700 CDD:278839 16/86 (19%)
FXa_inhibition 707..742 CDD:291342
CUB 747..856 CDD:278839
CUB 860..973 CDD:278839
CG9372NP_649132.1 CLIP 87..132 CDD:197829 17/107 (16%)
Tryp_SPc 173..402 CDD:214473
Tryp_SPc 176..402 CDD:238113
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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