DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BMP1 and Jon65Aiv

DIOPT Version :9

Sequence 1:	NP_006120.1	Gene:	BMP1 / 649	HGNCID:	1067	Length:	986	Species:	Homo sapiens
Sequence 2:	NP_648012.1	Gene:	Jon65Aiv / 38682	FlyBaseID:	FBgn0250815	Length:	271	Species:	Drosophila melanogaster

Alignment Length:	162	Identity:	36/162 - (22%)
Similarity:	54/162 - (33%)	Gaps:	63/162 - (38%)

- Green bases have known domain annotations that are detailed below.

Human   499 HSESSTLIGRYCGYEKP---DDIK-------STSSRL-----------WLKFVSDGSI------- 535
            |:.||:.|..:.|:...   :||.       |:|||:           :..||.|.::
  Fly   106 HTVSSSDIIIHSGWNSANLRNDISLIKIPATSSSSRISAVKLPSISNSYSTFVGDVAVASGWGRT 170

Human   536 --NKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPD----------KRRCE 588
              ..:|.|.| .:.||              |..:.:.||:...|..:..|          |..|.
  Fly   171 SDTSSGVATN-LQYVD--------------LTVITNTKCAQTYGTSVVTDSTLCVATTDAKSTCN 220

Human   589 AACGGFLTKLNGS----IT----SPGWPKEYP 612
            ...||.|...:.|    :|    |.|..|.||
  Fly   221 GDSGGPLVLKSSSEQIGLTSFGASAGCEKGYP 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BMP1	NP_006120.1	ZnMc_BMP1_TLD	121..320	CDD:239808
		Astacin	128..321	CDD:279708
		CUB	322..431	CDD:278839
		CUB	435..544	CDD:278839	16/74 (22%)
		FXa_inhibition	555..587	CDD:291342	6/41 (15%)
		CUB	591..700	CDD:278839	10/30 (33%)
		FXa_inhibition	707..742	CDD:291342
		CUB	747..856	CDD:278839
		CUB	860..973	CDD:278839
Jon65Aiv	NP_648012.1	Tryp_SPc	37..265	CDD:214473	36/162 (22%)
Jon65Aiv	NP_648012.1	Tryp_SPc	38..268	CDD:238113	36/162 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910