DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BMP1 and CG8172

DIOPT Version :9

Sequence 1:	NP_006120.1	Gene:	BMP1 / 649	HGNCID:	1067	Length:	986	Species:	Homo sapiens
Sequence 2:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster

Alignment Length:	155	Identity:	37/155 - (23%)
Similarity:	49/155 - (31%)	Gaps:	36/155 - (23%)

- Green bases have known domain annotations that are detailed below.

Human    20 GRPLDL----------ADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAVDL 74
            |:||||          .|...|..|...:.|:|....   ...|.||   ..||.....:....|
  Fly    96 GKPLDLCSGGMIWSCCVDKDLDAEESPHAAPVNNTSD---IIHLHDI---YPDLSTNANKPQHHL 154

Human    75 RRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRRAATSRPERVWPDGVIPFVI 139
            ..|:....|   |.|..:||.|..:....|             |....|.||...  .|..|:..
  Fly   155 HHHSGNGLS---AAPSTSSTASSSARPAYP-------------SSYYGTKRPTHY--SGSNPYKP 201

Human   140 GGNFTGSQR--AVFRQAMRHWEKHT 162
            |.:..||.|  :....::..||..|
  Fly   202 GSSAGGSSRPSSSSSSSLNSWEHET 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BMP1	NP_006120.1	ZnMc_BMP1_TLD	121..320	CDD:239808	12/44 (27%)
		Astacin	128..321	CDD:279708	9/37 (24%)
		CUB	322..431	CDD:278839
		CUB	435..544	CDD:278839
		FXa_inhibition	555..587	CDD:291342
		CUB	591..700	CDD:278839
		FXa_inhibition	707..742	CDD:291342
		CUB	747..856	CDD:278839
		CUB	860..973	CDD:278839
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910