DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BMP1 and CG3355

DIOPT Version :9

Sequence 1:	NP_006120.1	Gene:	BMP1 / 649	HGNCID:	1067	Length:	986	Species:	Homo sapiens
Sequence 2:	NP_608848.1	Gene:	CG3355 / 33667	FlyBaseID:	FBgn0031619	Length:	314	Species:	Drosophila melanogaster

Alignment Length:	127	Identity:	33/127 - (25%)
Similarity:	44/127 - (34%)	Gaps:	35/127 - (27%)

- Green bases have known domain annotations that are detailed below.

Human   533 GSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYK--------CSCDPGYELAPDKRRCEA 589
            |.|.:.|...|:.:||:.....|     .:|..|  .||        |:   |......|..|:.
  Fly   204 GLIKEGGVTSNYLQEVNVPVITN-----AQCRQT--RYKDKIAEVMLCA---GLVQQGGKDACQG 258

Human   590 ACGGFLT------KLNGSITSPGWPKEYPPNKNCIWQLVAPTQY-RISLQFDFFETEGNDVC 644
            ..||.|.      ||.| :.|.|:        .|. |..||..| |:|...|:......|.|
  Fly   259 DSGGPLIVNEGRYKLAG-VVSFGY--------GCA-QKNAPGVYARVSKFLDWIRKNTADGC 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BMP1	NP_006120.1	ZnMc_BMP1_TLD	121..320	CDD:239808
		Astacin	128..321	CDD:279708
		CUB	322..431	CDD:278839
		CUB	435..544	CDD:278839	3/10 (30%)
		FXa_inhibition	555..587	CDD:291342	8/39 (21%)
		CUB	591..700	CDD:278839	18/61 (30%)
		FXa_inhibition	707..742	CDD:291342
		CUB	747..856	CDD:278839
		CUB	860..973	CDD:278839
CG3355	NP_608848.1	Tryp_SPc	75..302	CDD:214473	31/117 (26%)
CG3355	NP_608848.1	Tryp_SPc	76..305	CDD:238113	31/120 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910