Protein Alignment chico and si:ch73-335l21.1

DIOPT Version :9

• Sequence 1: NP_001188772.1
• Gene: chico / 64880
• FlyBaseID: FBgn0024248
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: XP_021333440.1
• Gene: si:ch73-335l21.1 / 794738
• ZFINID: ZDB-GENE-130530-591
• Length: 1249
• Species: Danio rerio
• Alignment Length: 1178
• Identity: 256/1178 - (21%)
• Similarity: 421/1178 - (35%)
• Gaps: 373/1178 - (31%)

  Fly     5 SDDGMALSGYLKKLKTMKKKFFVLYEETSTSAARLEYYDTEKKFLQRAE-PKRVIYLKNCFNINR 68
            |.:.:..||||:|.|:|.:::|||...:....||||||::||||..:|. ||:.:.|:.|||||:
Zfish    10 STEDVRRSGYLRKQKSMHRRYFVLRAASERGPARLEYYESEKKFRGKAPVPKKALALETCFNINK 74

  Fly    69 RLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVLQRN----IANSNGTAH---SP---YD 123
            |.|:|::.:|||.:|...|.:..|||.|..:|...::.||..    ..|:||..:   ||   :.
Zfish    75 RADSKNKHMIVLYTRAESFVVAAENEADQEEWYQAMVELQCKSKALCENANGGDYGVPSPGPAFK 139

  Fly   124 HVWQVVIQKKGISEKVGITGTYHCCLTSKSLTFVCIGPEKTPNGEDRVASIEILLTTIRRCGHAS 188
            .||||.:..||:.:...:.|.|..|||.|::.||.:       ..|.|| :.:.|..:|||||:
Zfish   140 EVWQVKVWPKGLGQAKNLVGIYRLCLTEKTVNFVKL-------NSDAVA-VVLQLMNVRRCGHS- 195

  Fly   189 PQCIFYVELGRQSVLGSGDLWMETDNAAIATNMHNTILSAMSAKTESNTNLINVYQNRPDLSHEP 253
             :..|:||:||.:|.|.|:.||:.|::.:|.|||.|:|.||.|.:|.
Zfish   196 -ENFFFVEVGRSAVTGPGEFWMQVDDSVVAQNMHETLLEAMKALSEE------------------ 241

  Fly   254 MRKRSSS---------ANEASKPINVNVIQNSQN-------------------SLELRSCSSPHN 290
            .|:||.|         ...||.||:|...::..|                   :....:.|....
Zfish   242 FRQRSKSQSTAAGAGGGTTASNPISVPSRRHHPNPPPSQVGFTRRPRTEPPGSTAGCNNTSPASR 306

  Fly   291 YGFGRER---------------------CDSLPTRNGTLSESSNQTYFGSNHGLRSNTISGIRP- 333
            :.|.|.|                     |.| ||.||::|.:..         |||.::....|
Zfish   307 HSFPRTRTSSDGAKVDDGGCATTGEIMPCSS-PTTNGSVSNTPI---------LRSTSVRASTPV 361

  Fly   334 -------HSTNKHSNSPTFTMP---LRCSESEESSISVDESDDNGSFSHY-RLNTRSSETAIPEE 387
                   .||:..:.|...:||   :..||...:......|....:.|.| ||..|....:   .
Zfish   362 KAQHALMRSTSTPAPSAAPSMPSGSVHGSEFCATGTGTGNSGGGANGSMYSRLPLRQPSVS---G 423

  Fly   388 NIDDFASAELF-------SKVT------------EQNVSDE--NYIPMNPVNPTDAIHEKEKADM 431
            ::.|:.|::.:       |.:|            ..::.||  |||.|:
Zfish   424 SLSDYGSSDEYGSSPGEHSLLTPTMQAGFTASSGSNSLGDEASNYILMS---------------- 472

  Fly   432 QRLEDASLHFNFPEHASEKLAKDFDLDSDNQCCRPIRAYSIGNKVEHLKFNKRLGHLNDTGQNPN 496
            ||   .|......::|..:..:.....|..:|....|..|....:..:.. :||..|...|:...
Zfish   473 QR---GSSKSQTSQNALPQTRRVLRRSSSRECEAERRIMSKRASLPPMAL-ERLAPLRRAGEEAV 533

  Fly   497 RVRAYSVGSKSKIPRCDLQRVVLVEDNKHEFTANRSQSSITKEGTSY-----------GSSANRQ 550
            ....|::.:::              .::..|.| |..|..:..||.|           |||
Zfish   534 EEDDYAIMNQT--------------SSRESFVA-RQDSGPSTSGTGYLEVAAEIKGDGGSS---- 579

  Fly   551 KKSTSAPLLSLKNQINSDRMSDLMEIDFSQATNLEKQKFIKNNEIPKYIENVFPKAPRTDSSSLT 615
            ....:|.:...|..:::..||.|..:                         ..|....:.|.|:|
Zfish   580 DTGITAVIGGAKGAVDNGYMSMLPGV-------------------------TAPPVSLSHSLSVT 619

  Fly   616 LHATSQK--DIFNGTKLNNTAI--------TSEDGYLEMKPVGNGYTPSSNCLP----------- 659
            :..:..|  |.:.....||:..        :..|||:.|       :|:|:|.|
Zfish   620 VSDSDSKSADDYMAMTPNNSISPPRQIRPPSGTDGYMMM-------SPNSSCSPDQRGVPTAWIG 677

  Fly   660 -MKVEKLKLSDYQTAPPLTATAAPVHDLNKISTYNISAEKWREQPSRSEEKKSNSPLNDNTFS-- 721
             ...:....|||....|::|.:|             ::.....:|....::.||.|.....:|
Zfish   678 SSSADSRTGSDYMNMSPISARSA-------------NSTPPPPEPHTPSDQHSNQPQPKMVYSYY 729

  Fly   722 SKPTNVESTSKSHDVHSANQIDCEKVCAQSSDKLNNHLADKIVENNNLDIGG----------HEE 776
            |.|.:.:..:.:|              .:.......||.     |....|||          |:|
Zfish   730 SLPRSYKHNTSTH--------------FEEGPGRGKHLV-----NGGKGIGGGRGLCNSKSKHQE 775

  Fly   777 KKLV--H-SISSEDYTQIKDKSNDFTKFNEAGYKILQIKSDSSLISSKLYQKGI----------- 827
             .||  | |:||..|:.....|.   ...|...|.::....::.:::|..::|.
Zfish   776 -PLVGRHLSLSSSSYSSSSASSE---SLGEGEEKAIKGTGGAAGVTAKDIERGSLQQRQGSGRAK 836

  Fly   828 --HKDNLERSQRL---TESVNTIP-------------------------------DNATATAVSS 856
              |..:..|...|   ....||:|                               .|.|......
Zfish   837 QGHSGHRGRPLSLFVDVNKANTLPRVRETPLLPEPKSPGEYVSIEFKGERNQKAEGNGTRGFRQD 901

  Fly   857 SSL-TKFNINSAKPAAA-------ADSRSTGTDPSTPQNI-------------LQIKDLNFPSRS 900
            :|| ...:.:..:|.:.       :.|.||...|||....             :.:..|.|||..
Zfish   902 ASLPPSSHRHLPRPTSCVAGFLQFSQSSSTPIPPSTASEYVNMELGVSLSPSPISLTPLGFPSFP 966

  Fly   901 SSRI---SQPELH--YASLDLPHCSGQNPAKYLKRGSRESPPVSACPEDGNT-----YAKIDFDQ 955
            :..:   :.|:.|  :.|..|.....:.  :..:|.||:    .:.|:.|::     |.|:.|..
Zfish   967 TPPVTPAAAPKAHDEHRSTVLNDIGAER--EMAQRKSRQ----GSVPQSGDSPTCGDYTKMAFSL 1025

  Fly   956 SDSSSSSS 963
            :..|:.||
Zfish  1026 NSGSTLSS 1033

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chico	NP_001188772.1	PH_IRS	7..112	CDD:269959	44/109 (40%)
		PH	25..104	CDD:278594	35/79 (44%)
		PTB_IRS	122..235	CDD:269915	43/112 (38%)
si:ch73-335l21.1	XP_021333440.1	PH_IRS	12..114	CDD:269959	42/101 (42%)
		PTB_IRS	138..241	CDD:269915	43/112 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586780
Domainoid	1	1.000	94	1.000	Domainoid score	I7398
eggNOG	1	0.900	-	-		E1_28N3R
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001178
OrthoInspector	1	1.000	-	-		otm24799
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10614
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1499
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.890