Protein Alignment Adgf-A2 and YJL070C

DIOPT Version :10

• Sequence 1: NP_525020.2
• Gene: Adgf-A2 / 64879
• FlyBaseID: FBgn0043025
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_012465.3
• Gene: YJL070C / 853375
• SGDID: S000003606
• Length: 888
• Species: Saccharomyces cerevisiae
• Alignment Length: 569
• Identity: 110/569 - (19%)
• Similarity: 179/569 - (31%)
• Gaps: 212/569 - (37%)

  Fly    73 NLTSEERHARLRQIYIEKERRQRLGSR----MGLSPLEEEANDRLMAI--RQVDEEFYNLWRN-- 129
            ||..|      |.:|.:.|..::|..|    .|.|     :||:.:||  :.:|:||.:.:||
Yeast   365 NLEPE------RIVYQDPETSRKLSLRDIFQFGCS-----SNDQPIAIGLKLIDDEFLDWYRNIY 418

  Fly   130 ---YHSQPPPFLKHLNIIDTNLYAAL--KSMPKGGLLHVHDSGMLRMEILIDLIYR-DNLWVCVN 188
               ||..|            |..|.|  |.|              |..:|..:... ||.
Yeast   419 LIDYHLTP------------NKVAKLVGKEM--------------RFYLLAKVFLEFDNF----- 452

  Fly   189 LEQDFEDFRFSRYFPHIPPAEDYQCNWMLMSNFFQLESRLEFENRLRKTLTVRPEGYKSSSELAR 253
            :|.::....|.:|..||.....||...:.::  ||..|..|             :.||..|:...
Yeast   453 IEGEYLAEIFIKYVIHILEKSKYQLAQVSVN--FQFYSSGE-------------DWYKKFSQWLL 502

  Fly   254 HLRRHQRIIHGLITFRPIWSEFIFTMLSDFYADGVHYVELRSSLPNMYDLDGNNFTILETAEA-- 316
            ..:        |:::...|:..|..:....:.:.|     .|:.....||..|....||..:.
Yeast   503 RWK--------LVSYNIRWNIQIARIFPKLFKENV-----VSNFQEFLDLIFNPLFTLEKEQLPI 554

  Fly   317 -----------------LVSVSNIFKNS----FKDFIGIK--------------------LIYAP 340
                             :.|:..:.|.|    :|:|..:.                    .||..
Yeast   555 DSSVNTDIIGLQFFLSNVCSMDLVIKESDEYYWKEFTDMNCKPKFWTAQGDNPTVAHYMYYIYKS 619

  Fly   341 SRNLNDSRMDEYLENARLLKLHFPNFFA---------GFDLNTFGDE-----CNL---------- 381
            ...:|..| .:.|:|...|:    |:.:         |.|| .|.|:     |||
Yeast   620 LAKVNFLR-SQNLQNTITLR----NYCSPLSSRTSQFGVDL-YFTDQVESLVCNLLLCNGGLLQV 678

  Fly   382 -PLLENVTQLLRIGKNIDFY-FHAGESRCPDSSRPDANLLEALLLQSKRI-------GNAVNLPF 437
             ||.:..|.:..:     || |.......|.||....|..::..|::|.:       .:......
Yeast   679 EPLWDTATMIQYL-----FYLFQIPILAAPLSSVSLLNSQKSTFLKNKNVLLEHDYLKDQETAKI 738

  Fly   438 HP------------EIMKVMKRLSIAVEICPLSNHYLQYFNDFRQHP--AAYLIAAGFPIVIGSD 488
            :|            |....||...:.::| .||:..:.|.:.:...|  ..|.:||...::..:|
Yeast   739 NPSRDITVGEQRSYETNPFMKMFKMGLKI-SLSSKSILYNSSYTLEPLIEEYSVAASIYLLNPTD 802

  Fly   489 -----------------YPCFW-----NSAPLTDDFYVAFVGVISGWGD 515
                             |...|     ..||    ::...||.|..|.|
Yeast   803 LCELSRTSVLSSGYEGWYKAHWIGVGVKKAP----YFEENVGGIDNWYD 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-A2	NP_525020.2	A_deaminase_N	59..152	CDD:462481	24/89 (27%)
		ADGF	135..548	CDD:238646	88/496 (18%)
YJL070C	NP_012465.3	metallo-dependent_hydrolases	281..873	CDD:469705	110/569 (19%)