Protein Alignment Adgf-A2 and Ampd2

DIOPT Version :10

• Sequence 1: NP_525020.2
• Gene: Adgf-A2 / 64879
• FlyBaseID: FBgn0043025
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001095151.1
• Gene: Ampd2 / 362015
• RGDID: 2110
• Length: 824
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 95/521 - (18%)
• Similarity: 181/521 - (34%)
• Gaps: 151/521 - (28%)

  Fly    92 RRQRLGSRMGLSPLEEEANDRLMAIRQV-DEEFYNLWRNYHSQPPPFLKHLNIIDTNLYAALKSM 155
            |.|.|.|:..:..|..|..: |.|.::| ..:|||:.:               :||
  Rat   324 RLQYLSSKFQMHVLLNEMKE-LAAQKKVPHRDFYNIRK---------------VDT--------- 363

  Fly   156 PKGGLLHVHDSGMLRMEILIDLIYR---DNLWVCVNLEQD--------FEDF------------- 196
                  |:|.|..:..:.|:..|.|   .:|...|::||.        ||..
  Rat   364 ------HIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLD 422

  Fly   197 ---------RFSRYFPHIPPAEDYQCNWMLMSNFFQLESRLE---FENRLRKTLTVRPEGYKSSS 249
                     ||.::.....|..:.    :|...|.:.::::.   |.:.:::.::...|....::
  Rat   423 VHADRNTFHRFDKFNAKYNPIGES----VLREIFIKTDNKISGKYFAHIIKEVMSDLEESKYQNA 483

  Fly   250 ELARHLRRHQRIIHGLITFRPIWSEFIFTMLSDFYADGVHYVELR--SSLPNMYDLDGNNFTILE 312
            ||       :..|:|  ..|..|.:.....::    ..||...:|  ..:|.::|       :..
  Rat   484 EL-------RLSIYG--RSRDEWDKLARWAVN----HRVHSPNVRWLVQVPRLFD-------VYR 528

  Fly   313 TAEALVSVSNIFKNSFKDFIGIKLIYAPSRNLNDSRMDEYLENARLLKLHFPNFFAGFDL----- 372
            |...|.:...:.:|.|     :.|..|.....:...:..:||:.           .|||.
  Rat   529 TKGQLANFQEMLENIF-----LPLFEATVHPASHPELHLFLEHV-----------DGFDSVDDES 577

  Fly   373 ----NTFGDECNLP-----------------LLENVTQLLRIGKNIDFYFHAGESRCPDSSRPDA 416
                :.|..|..||                 ...|:..|..:.:...|:.......|.::. |..
  Rat   578 KPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAG-PIH 641

  Fly   417 NLLEALLLQSKRIGNAVNLPFHPEIMKVMKRLSIAVEICPLSNHYLQYFNDFRQHPAAYLIAAGF 481
            :|:.|.:| ::.|.:.:.|...|.:..:.....|.:.:.||||:.|  |..:.::|....::.|.
  Rat   642 HLVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSL--FLSYHRNPLPEYLSRGL 703

  Fly   482 PIVIGSDYPC--FWNSAPLTDDFYVAF-VGVISGWGDLRLLKQFALNSFLFSSLSETEKNMAVSK 543
            .:.:.:|.|.  .:...||.:::.:|. |..:|...    :.:.|.||.|.|..|...|    |.
  Rat   704 MVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCD----MCELARNSVLMSGFSHKVK----SH 760

  Fly   544 W 544
            |
  Rat   761 W 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-A2	NP_525020.2	A_deaminase_N	59..152	CDD:462481	14/60 (23%)
		ADGF	135..548	CDD:238646	83/477 (17%)
Ampd2	NP_001095151.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		AMP_deaminase	163..806	CDD:437158	95/521 (18%)