Protein Alignment Adgf-A2 and AMPD2

DIOPT Version :9

• Sequence 1: NP_525020.2
• Gene: Adgf-A2 / 64879
• FlyBaseID: FBgn0043025
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001355738.1
• Gene: AMPD2 / 271
• HGNCID: 469
• Length: 825
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 94/520 - (18%)
• Similarity: 183/520 - (35%)
• Gaps: 149/520 - (28%)

  Fly    92 RRQRLGSRMGLSPLEEEANDRLMAIRQV-DEEFYNLWRNYHSQPPPFLKHLNIIDTNLYAALKSM 155
            |.|.|.|:..:..|..|..: |.|.::| ..:|||:.:               :||
Human   324 RLQYLSSKFQMHVLLNEMKE-LAAQKKVPHRDFYNIRK---------------VDT--------- 363

  Fly   156 PKGGLLHVHDSGMLRMEILIDLIYR---DNLWVCVNLEQD--------FEDF------------- 196
                  |:|.|..:..:.|:..|.|   .:|...|::||.        ||..
Human   364 ------HIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLD 422

  Fly   197 ---------RFSRYFPHIPPAEDYQCNWMLMSNFFQLESRLE---FENRLRKTLTVRPEGYKSSS 249
                     ||.::.....|..:.    :|...|.:.::|:.   |.:.:::.::...|....::
Human   423 VHADRNTFHRFDKFNAKYNPIGES----VLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNA 483

  Fly   250 ELARHLRRHQRIIHGLITFRPIWSEFI-FTMLSDFYADGVHYVELRSSLPNMYDLDGNNFTILET 313
            ||       :..|:|  ..|..|.:.. :.::...::..|.::   ..:|.::|       :..|
Human   484 EL-------RLSIYG--RSRDEWDKLARWAVMHRVHSPNVRWL---VQVPRLFD-------VYRT 529

  Fly   314 AEALVSVSNIFKNSFKDFIGIKLIYAPSRNLNDSRMDEYLENARLLKLHFPNFFAGFDL------ 372
            ...|.:...:.:|.|     :.|..|.....:...:..:||:.           .|||.
Human   530 KGQLANFQEMLENIF-----LPLFEATVHPASHPELHLFLEHV-----------DGFDSVDDESK 578

  Fly   373 ---NTFGDECNLP-----------------LLENVTQLLRIGKNIDFYFHAGESRCPDSSRPDAN 417
               :.|..|..||                 ...|:..|..:.:...|:.......|.::. |..:
Human   579 PENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAG-PIHH 642

  Fly   418 LLEALLLQSKRIGNAVNLPFHPEIMKVMKRLSIAVEICPLSNHYLQYFNDFRQHPAAYLIAAGFP 482
            |:.|.:| ::.|.:.:.|...|.:..:.....|.:.:.||||:.|  |..:.::|....::.|..
Human   643 LVSAFML-AENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSL--FLSYHRNPLPEYLSRGLM 704

  Fly   483 IVIGSDYPC--FWNSAPLTDDFYVAF-VGVISGWGDLRLLKQFALNSFLFSSLSETEKNMAVSKW 544
            :.:.:|.|.  .:...||.:::.:|. |..:|...    :.:.|.||.|.|..|...|    |.|
Human   705 VSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCD----MCELARNSVLMSGFSHKVK----SHW 761

  Fly   545  544
            Human   762  761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-A2	NP_525020.2	A_deaminase_N	52..152	CDD:285627	14/60 (23%)
		adm_rel	83..556	CDD:273620	94/520 (18%)
		ADGF	135..548	CDD:238646	82/476 (17%)
AMPD2	NP_001355738.1	AMPD	301..797	CDD:238644	94/520 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810