Protein Alignment Adgf-A2 and MAPDA

DIOPT Version :10

• Sequence 1: NP_525020.2
• Gene: Adgf-A2 / 64879
• FlyBaseID: FBgn0043025
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001311295.1
• Gene: MAPDA / 161823
• HGNCID: 31853
• Length: 355
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 65/273 - (23%)
• Similarity: 107/273 - (39%)
• Gaps: 43/273 - (15%)

  Fly   233 RLRKTLTVRPEGYKSSSELARHLRR--HQRIIHGLITFRPIWSEFIFTMLSD----FYADGVHYV 291
            ::...:||..:|.|.:.|....:.:  ||      :|..|   |.|..:..|    |..|||.|:
Human    47 KIHDQMTVIDKGKKRTLEECFQMFQTIHQ------LTSSP---EDILMVTKDVIKEFADDGVKYL 102

  Fly   292 ELRSSLPNMYDLDGNNFTILETAEALVSVSNIFKNSFKDFIGIKLIY--APSRNLNDSRMDEYLE 354
            ||||: |..     .|.|.:.....:.|:....|.|.::.:.|.:.|  |..|........|.::
Human   103 ELRST-PRR-----ENATGMTKKTYVESILEGIKQSKQENLDIDVRYLIAVDRRGGPLVAKETVK 161

  Fly   355 NARLLKLHFPNFFAGFDLN---TFGDECNL--PLLENVTQLLRIGKNIDFYFHAGESRCPDSSRP 414
            .|....|.......|.||:   |.|...:.  ||||.....|::..::        |..|:..:.
Human   162 LAEEFFLSTEGTVLGLDLSGDPTVGQAKDFLEPLLEAKKAGLKLALHL--------SEIPNQKKE 218

  Fly   415 DANLLEALLLQSKRIGNAVNLPFHP----EIMKVMKRLSIAVEICPLSNHYLQYFNDFRQHPAAY 475
            ...||:.|   ..|||:...|....    :::..:::..|.:|:|..||...|....:.||...:
Human   219 TQILLDLL---PDRIGHGTFLNSGEGGSLDLVDFVRQHRIPLELCLTSNVKSQTVPSYDQHHFGF 280

  Fly   476 LIAAGFPIVIGSD 488
            ..:...|.||.:|
Human   281 WYSIAHPSVICTD 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-A2	NP_525020.2	A_deaminase_N	59..152	CDD:462481
		ADGF	135..548	CDD:238646	65/273 (24%)
MAPDA	NP_001311295.1	ADA_AMPD	18..345	CDD:238250	65/273 (24%)