Protein Alignment cpx and CPLX3

DIOPT Version :9

• Sequence 1: NP_001262248.1
• Gene: cpx / 64877
• FlyBaseID: FBgn0041605
• Length: 157
• Species: Drosophila melanogaster
• Sequence 2: NP_001025176.1
• Gene: CPLX3 / 594855
• HGNCID: 27652
• Length: 158
• Species: Homo sapiens
• Alignment Length: 132
• Identity: 44/132 - (33%)
• Similarity: 62/132 - (46%)
• Gaps: 21/132 - (15%)

  Fly     3 AFIAKQMVGNQLSAVKGAVGGDGGDDGD-DKEKAE------EEERERQEAIKEAEDRRKEKHRKM 60
            ||:.|.|||.||..:.|::|| |.|.|| ||..||      ||..|.|:.:.|.:..|..:..:.
Human     2 AFMVKTMVGGQLKNLTGSLGG-GEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQR 65

  Fly    61 EEEREKMRQDIRDKYNIKKKE----EIVEAAPQEEPNPLMRKKKTPEELAAEAEQEELDDFTSKS 121
            :.||..:|...||||.:.|.|    :|..|....|         .|.|||...|::..::....|
Human    66 KAERATLRSHFRDKYRLPKNETDESQIQMAGGDVE---------LPRELAKMIEEDTEEEEEKAS 121

  Fly   122 LL 123
            :|
Human   122 VL 123

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cpx	NP_001262248.1	Synaphin	2..124	CDD:283491	44/132 (33%)
CPLX3	NP_001025176.1	Synaphin	1..139	CDD:310434	44/132 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	13..47		14/34 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..99		8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155032
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16705
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030