Protein Alignment cpx and CPLX4

DIOPT Version :9

• Sequence 1: NP_001262248.1
• Gene: cpx / 64877
• FlyBaseID: FBgn0041605
• Length: 157
• Species: Drosophila melanogaster
• Sequence 2: NP_857637.1
• Gene: CPLX4 / 339302
• HGNCID: 24330
• Length: 160
• Species: Homo sapiens
• Alignment Length: 132
• Identity: 34/132 - (25%)
• Similarity: 56/132 - (42%)
• Gaps: 32/132 - (24%)

  Fly     3 AFIAKQMVGNQLSAVKGAVGGDGGDDGDDKEK------------AEEEERERQEAIKEAEDRRKE 55
            ||:.|.|:.||:..:     |.||...::||:            ..||..|.|:.:.|.:..|..
Human     2 AFLMKSMISNQVKNL-----GFGGGSEENKEEGGASDPAAAQGMTREEYEEYQKQMIEEKMERDA 61

  Fly    56 KHRKMEEEREKMRQDIRDKYNIKKKE----EIVEAAPQEEPNPLMRKKKTPEEL--AAEAEQEEL 114
            ...:.:.||..:|..:|:||.:.|.|    :|..|....:         .||:|  ..:.:|||.
Human    62 AFTQKKAERACLRVHLREKYRLPKSEMDENQIQMAGDDVD---------LPEDLRKMVDEDQEEE 117

  Fly   115 DD 116
            :|
Human   118 ED 119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cpx	NP_001262248.1	Synaphin	2..124	CDD:283491	34/132 (26%)
CPLX4	NP_857637.1	Synaphin	1..140	CDD:399088	34/132 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	14..51		9/41 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155029
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16705
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030