DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cpx and Cplx3

DIOPT Version :9

Sequence 1:	NP_001262248.1	Gene:	cpx / 64877	FlyBaseID:	FBgn0041605	Length:	157	Species:	Drosophila melanogaster
Sequence 2:	NP_666335.1	Gene:	Cplx3 / 235415	MGIID:	2384571	Length:	158	Species:	Mus musculus

Alignment Length:	130	Identity:	46/130 - (35%)
Similarity:	61/130 - (46%)	Gaps:	23/130 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AFIAKQMVGNQLSAVKGAVGGDGGDDGD-DKEKAE------EEERERQEAIKEAEDRRKEKHRKM 60
            ||:.|.|||.||..:.|::|| |.|.|| ||..||      ||..|.|:.:.|.:..|..:..:.
Mouse     2 AFMVKSMVGGQLKNLTGSLGG-GEDKGDGDKSAAEAQGMSREEYEEYQKQLVEEKMERDAQFTQR 65

  Fly    61 EEEREKMRQDIRDKYNIKKKE----EIVEAAPQEEPNPLMRKKKTPEELA--AEAEQEELDDFTS 119
            :.||..:|...||||.:.|.|    :|..|....|         .|.|||  .|.:.||.:|..|
Mouse    66 KAERATLRSHFRDKYRLPKNETDESQIQLAGGDVE---------LPRELAKMIEEDTEEEEDKAS 121

Fly 120 119
Mouse 122 121

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cpx	NP_001262248.1	Synaphin	2..124	CDD:283491	46/130 (35%)
Cplx3	NP_666335.1	Synaphin	1..139	CDD:399088	46/130 (35%)
Cplx3	NP_666335.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	14..47		13/33 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845493
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16705
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030