Protein Alignment cpx and Cplx2

DIOPT Version :9

• Sequence 1: NP_001262248.1
• Gene: cpx / 64877
• FlyBaseID: FBgn0041605
• Length: 157
• Species: Drosophila melanogaster
• Sequence 2: NP_001349147.1
• Gene: Cplx2 / 12890
• MGIID: 104726
• Length: 134
• Species: Mus musculus
• Alignment Length: 140
• Identity: 55/140 - (39%)
• Similarity: 76/140 - (54%)
• Gaps: 15/140 - (10%)

  Fly     4 FIAKQMVGNQLSAVKGAVGGDGGDDGDDKEKAEEEERERQEAIKEAEDRRKEKHRKMEEEREKMR 68
            |:.||.:|.....:...:||:...|.|    |:::|.|||||:::.|:.||.||.:||.||||:|
Mouse     3 FVMKQALGGATKDMGKMLGGEEEKDPD----AQKKEEERQEALRQQEEERKAKHARMEAEREKVR 63

  Fly    69 QDIRDKYNIKKKE--EIVEAAPQEEP--NPLMRKKKT-PEELAAEAEQEELDDFTSKSLLPLSSA 128
            |.|||||.:||||  |..|.|..|:|  ..|.|.||. |.....|.|:||      :|:|.....
Mouse    64 QQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEE------ESILDTVLK 122

  Fly   129 VEPGSASGIY 138
            ..||....::
Mouse   123 YLPGPLQDMF 132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cpx	NP_001262248.1	Synaphin	2..124	CDD:283491	52/124 (42%)
Cplx2	NP_001349147.1	Synaphin	1..133	CDD:399088	55/140 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..114		51/120 (43%)
		Interaction with the SNARE complex. /evidence=ECO:0000250	41..97		28/55 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845494
Domainoid	1	1.000	83	1.000	Domainoid score	I8355
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I5173
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44305
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2464
SonicParanoid	1	1.000	-	-		X2910
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.980