Protein Alignment cpx and Cplx1

DIOPT Version :9

• Sequence 1: NP_001262248.1
• Gene: cpx / 64877
• FlyBaseID: FBgn0041605
• Length: 157
• Species: Drosophila melanogaster
• Sequence 2: NP_031782.3
• Gene: Cplx1 / 12889
• MGIID: 104727
• Length: 134
• Species: Mus musculus
• Alignment Length: 140
• Identity: 57/140 - (40%)
• Similarity: 74/140 - (52%)
• Gaps: 15/140 - (10%)

  Fly     4 FIAKQMVGNQLSAVKGAVGGDGGDDGDDKEKAEEEERERQEAIKEAEDRRKEKHRKMEEEREKMR 68
            |:.||.:|.....:...:|||...|.|    |.::|.|||||:::||:.||.|:.|||.|||.||
Mouse     3 FVMKQALGGATKDMGKMLGGDEEKDPD----AAKKEEERQEALRQAEEERKAKYAKMEAEREVMR 63

  Fly    69 QDIRDKYNIKKKEE-IVEAAPQEEPN---PLMRKKKT-PEELAAEAEQEELDDFTSKSLLPLSSA 128
            |.|||||.|||||| ..||....|.|   .|.|.||. |.....|.|:|:      :|:|.....
Mouse    64 QGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEPEEED------ESILDTVIK 122

  Fly   129 VEPGSASGIY 138
            ..||....::
Mouse   123 YLPGPLQDMF 132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cpx	NP_001262248.1	Synaphin	2..124	CDD:283491	54/124 (44%)
Cplx1	NP_031782.3	Synaphin	1..133	CDD:399088	57/140 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..60		25/60 (42%)
		Interaction with the SNARE complex. /evidence=ECO:0000250	48..70		15/21 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..114		16/45 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845495
Domainoid	1	1.000	83	1.000	Domainoid score	I8355
eggNOG	1	0.900	-	-		E1_2CF74
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I5173
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44305
orthoMCL	1	0.900	-	-		OOG6_108742
Panther	1	1.100	-	-	O	PTHR16705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2464
SonicParanoid	1	1.000	-	-		X2910
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.780