Protein Alignment cpx and Cplx1

DIOPT Version :10

• Sequence 1: NP_001262248.1
• Gene: cpx / 64877
• FlyBaseID: FBgn0041605
• Length: 157
• Species: Drosophila melanogaster
• Sequence 2: NP_031782.3
• Gene: Cplx1 / 12889
• MGIID: 104727
• Length: 134
• Species: Mus musculus
• Alignment Length: 140
• Identity: 57/140 - (40%)
• Similarity: 74/140 - (52%)
• Gaps: 15/140 - (10%)

  Fly     4 FIAKQMVGNQLSAVKGAVGGDGGDDGDDKEKAEEEERERQEAIKEAEDRRKEKHRKMEEEREKMR 68
            |:.||.:|.....:...:|||...|.|    |.::|.|||||:::||:.||.|:.|||.|||.||
Mouse     3 FVMKQALGGATKDMGKMLGGDEEKDPD----AAKKEEERQEALRQAEEERKAKYAKMEAEREVMR 63

  Fly    69 QDIRDKYNIKKKEE-IVEAAPQEEPN---PLMRKKKT-PEELAAEAEQEELDDFTSKSLLPLSSA 128
            |.|||||.|||||| ..||....|.|   .|.|.||. |.....|.|:|:      :|:|.....
Mouse    64 QGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEPEEED------ESILDTVIK 122

  Fly   129 VEPGSASGIY 138
            ..||....::
Mouse   123 YLPGPLQDMF 132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cpx	NP_001262248.1	Synaphin	2..124	CDD:461755	54/124 (44%)
Cplx1	NP_031782.3	Synaphin	1..133	CDD:461755	57/140 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..60		25/60 (42%)
		Interaction with the SNARE complex. /evidence=ECO:0000250	48..70		15/21 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..114		16/45 (36%)