Protein Alignment disco-r and disco

DIOPT Version :9

• Sequence 1: NP_001259598.1
• Gene: disco-r / 64875
• FlyBaseID: FBgn0285879
• Length: 1311
• Species: Drosophila melanogaster
• Sequence 2: NP_001033847.1
• Gene: disco / 32579
• FlyBaseID: FBgn0000459
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 892
• Identity: 231/892 - (25%)
• Similarity: 326/892 - (36%)
• Gaps: 400/892 - (44%)

  Fly   278 MQPFDFRKISSAAALGAFGGPLPLPQSPTEFGQHHHHSQQQQHQHHLHRNQFFNAMAMAYHLPPP 342
            |.||    :|.|..||                 |..||.|..|.|                   .
  Fly     5 MNPF----MSPAYLLG-----------------HGPHSHQHVHSH-------------------L 29

  Fly   343 PPPPPPDSRSPPSPPPGVGQYQHQAGSGSGSGSGSGSGSSSGAGSVDDSAGKQQRNSDKVSASGS 407
            |..|.|::.||.|.|.|        .|||||||.:|||:.||
  Fly    30 PSHPQPNAASPASSPGG--------SSGSGSGSAAGSGTGSG----------------------- 63

  Fly   408 CSSSQRMTRLALSSNMRSSRKTPHSPGGGGAGGNGGSVGGGGGKRQWGSMPANLGTQFINPVTGK 472
                             ||.|                      .|:|||.|.||..|||||.|||
  Fly    64 -----------------SSLK----------------------PRRWGSPPINLAGQFINPATGK 89

  Fly   473 KRVQCNVCLKTFCDKGALKIHFSAVHLREMHKCTVDGCSMMFSSRRSRNRHSANPNPKLHSPHLR 537
            |||||::|.||||||||||||||||||||||||||:||:|:||||||||||||||||||||||:|
  Fly    90 KRVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVFSSRRSRNRHSANPNPKLHSPHIR 154

  Fly   538 RKISPHDGRSAQPHPLL---LQAPNGLMAGLAPFGSFPLLTPPPDLRH----HAMGGSGAGSGAG 595
            |||||||||:||..|:.   ..|....:||..|. :||.|.|||...|    :.|.|..||
  Fly   155 RKISPHDGRTAQQFPVFSPGTAAAAAAVAGRLPV-AFPGLLPPPPPHHGHHPYVMFGGQAG---- 214

  Fly   596 VGALELKHGQDYLQRSYLDAGRFEGQRRKLAMENEHTEDEDDDEILEVGIHMAG--DDDDDEADG 658
                  .||                                      :|:...|  |.|....|.
  Fly   215 ------LHG--------------------------------------LGLLSTGCQDPDSGSVDN 235

  Fly   659 DEDEDDDDPDGIVVVGDEIDS----MPLDHENDNDNENENDESDERSTSAVSSLSQTKEQSSPGK 719
            ::|.|.:|.:..|.|..:.:|    ...:.:.:::.:||.||....|.|..||.|
  Fly   236 EQDADPEDDNDFVYVDMQANSSSPAASSEDQEEHERDNEQDEEMHCSLSLASSSS---------- 290

  Fly   720 VVQSGLEECHTYAHAHAHALTHGHAHSLGHAHALAQMAANKRKRKSQNPVRCPVQSDENSGENSI 784
                                                :||:: :|.:..|:
  Fly   291 ------------------------------------IAADE-ERAADQPL--------------- 303

  Fly   785 DYDVAADLSIKKVRLPAQAAASAKESEVGESTKSIPSPPLTPYGDLRPVGLCIKTEQDHEQELDQ 849
                  |.|:.|.|                                       |:|||.|||.:|
  Fly   304 ------DFSLHKRR---------------------------------------KSEQDREQEQEQ 323

  Fly   850 EQGQERKREQEQEPEPDPVATASKSEMKLEEQETRPADKEDDNEED-----EQVSPPVVTTLDLS 909
            ||.:||:.|:|||.:.:                   :|||.:.|::     |:.||....::|
  Fly   324 EQEREREAEKEQEQDVE-------------------SDKEHEPEQEHELEREKRSPSDAFSMD-- 367

  Fly   910 RAAAAIKLEPLEEINYEADENRYVRIKQELMG---GDESLAEESSDKTANHNNNNNNNNNININ- 970
                                        :|:|   ..:|.|..|:..||..::.::::.:.:.|
  Fly   368 ----------------------------QLLGKRKRHDSTASSSACSTAAASSASSSSASASANP 404

  Fly   971 --NSVRLESDNGLEASELEERE---PEPETEIEPEHEHEHEPEPETEV-----------EVPEV- 1018
              .|::::.|...:::.:..|.   |.|..::|   ||.|....:|::           :.|..
  Fly   405 PQTSIKMDLDPDSDSAYMTSRRQMLPLPVLDLE---EHHHLRLLQTQMFAAAAAAAATSQAPPTA 466

  Fly  1019 ------PID--KENPLKCTACGEIFQNHFHLKTHHQSVHLKLHHKCNIDGCNAAFPSKRSRDRHS 1075
                  |:|  |::|...:...|::::.. |||.||..:   ||             .:.:.:|.
  Fly   467 FLPAGSPVDLAKDSPPMWSLLSEMYRSML-LKTQHQQYN---HH-------------HQLQQQHQ 514

  Fly  1076 SNLNLHRKLLSTSDDHGLLHAPVMPATDPLLELMSLNLNNNKSGFHH 1122
            ...:.|   |:.|..|...|.               :|.::..|.||
  Fly   515 QEQHHH---LTLSHHHQEQHH---------------HLGHHHMGHHH 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disco-r	NP_001259598.1	C2H2 Zn finger	1028..1053	CDD:275370	6/24 (25%)
		C2H2 Zn finger	1056..1083	CDD:275370	2/26 (8%)
disco	NP_001033847.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468780
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2C0EZ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7987
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D59377at33208
OrthoFinder	1	1.000	-	-		FOG0002551
OrthoInspector	1	1.000	-	-		otm26341
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR15021
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3798
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.920