DRSC/TRiP Functional Genomics Resources

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Protein Alignment MESK4 and aldh1a3

DIOPT Version :9

Sequence 1:NP_001262650.1 Gene:MESK4 / 64872 FlyBaseID:FBgn0043069 Length:280 Species:Drosophila melanogaster
Sequence 2:NP_001038210.1 Gene:aldh1a3 / 751785 ZFINID:ZDB-GENE-061128-2 Length:513 Species:Danio rerio


Alignment Length:264 Identity:48/264 - (18%)
Similarity:75/264 - (28%) Gaps:88/264 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSGTSTSERSNSEDSPLNPCLTEVLRNCANIQSLESLNYEYNDVLLTEDNVGKMITPNPYSFSGN 65
            |:...|.|..:|.::...|     |.....|..::......|:...|.....:..|.||.:....
Zfish     1 MAQNGTIENGDSRNTSPPP-----LPQPVKITEIKHTKIFINNEWHTSSKGKQFPTINPATGVKI 60

  Fly    66 ISISSCPSEDVSFSESILEDNGRISLAYENLKTIPR-----RLADKFAAQTKFLDLSHNDFRNLR 125
            ..|......||..:....:..|:....:..:....|     ||||....:...|....:......
Zfish    61 CDIEEADKADVDEAVKAAKAAGQRGSVWRRMDASSRGRLLNRLADLLERERAVLATLESKDTGKP 125

  Fly   126 FL-SFFEDLD-------------------TLILDRN---------VNLDINTFPY-LPSLRILWI 160
            || :||.|||                   |:.:|.|         :.:.....|: .|.|.::| 
Zfish   126 FLHAFFVDLDGSIKTLRYYAGWTDKIHGKTMPVDENFVCFTKHEPIGVCGAIIPWNFPLLMLMW- 189

  Fly   161 NNCDIANITDWIHRIERHCPALDQLSCMGN---------------------------PGIRTVFG 198
                            :..||   |:| ||                           ||:..|..
Zfish   190 ----------------KIAPA---LAC-GNTVVLKPAEQTPLTALHVAALIKEAGFPPGVVNVVP 234

  Fly   199 GQGP 202
            |.||
Zfish   235 GFGP 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MESK4NP_001262650.1 leucine-rich repeat 111..132 CDD:275378 5/21 (24%)
leucine-rich repeat 133..154 CDD:275378 6/49 (12%)
leucine-rich repeat 155..181 CDD:275378 2/25 (8%)
aldh1a3NP_001038210.1 ALDH_F1AB_F2_RALDH1 28..506 CDD:143459 41/232 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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