DRSC/TRiP Functional Genomics Resources

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Protein Alignment MESK4 and Aldh1a7

DIOPT Version :9

Sequence 1:NP_001262650.1 Gene:MESK4 / 64872 FlyBaseID:FBgn0043069 Length:280 Species:Drosophila melanogaster
Sequence 2:NP_036051.1 Gene:Aldh1a7 / 26358 MGIID:1347050 Length:501 Species:Mus musculus


Alignment Length:251 Identity:51/251 - (20%)
Similarity:77/251 - (30%) Gaps:89/251 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 SPLNPCLTEVLRNCANIQSLESLNYEYNDVL----------LTED-----------NVGKMITPN 58
            ||..|.:...|.|.....:...:|.|::|.:          .||:           :|.|.:...
Mouse     3 SPAQPAVPAPLANLKIQHTKIFINNEWHDSVSSKKFPVLNPATEEVICHVEEGDKADVDKAVKAA 67

  Fly    59 PYSFSGNISISSCPSEDVSFSE--------SILEDNGRISLAYENLKTIPRRLADKFAAQTKFLD 115
            ..:|    .|.| |...:..||        :.|.:..|:.||     |:....|.|..|....||
Mouse    68 RQAF----QIGS-PWRTMDASERGRLLNKLADLMERDRLLLA-----TMESMNAGKVFAHAYLLD 122

  Fly   116 LSHNDFRNLRFLSFFEDLDTLILDRNVNLDINTFPYLPSLRILWINNCDIANITDWIHRIERHCP 180
            :.    .:::.|.:|......|..:.:..|.|.|.|   .|...|..|  ..|..|      :.|
Mouse   123 VE----ISIKALQYFAGWADKIHGQTIPSDGNIFTY---TRREPIGVC--GQIIPW------NGP 172

  Fly   181 AL-------DQLSCMGN---------------------------PGIRTVFGGQGP 202
            .:       ..||| ||                           ||:..:..|.||
Mouse   173 LIIFTWKLGPALSC-GNTVVVKPAEQTPLTALHMASLIKEAGFPPGVVNIVPGYGP 227

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MESK4NP_001262650.1 leucine-rich repeat 111..132 CDD:275378 4/20 (20%)
leucine-rich repeat 133..154 CDD:275378 5/20 (25%)
leucine-rich repeat 155..181 CDD:275378 5/25 (20%)
Aldh1a7NP_036051.1 ALDH_F1AB_F2_RALDH1 15..494 CDD:143459 47/239 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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