DRSC/TRiP Functional Genomics Resources

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Protein Alignment MESK4 and ALDH2

DIOPT Version :9

Sequence 1:NP_001262650.1 Gene:MESK4 / 64872 FlyBaseID:FBgn0043069 Length:280 Species:Drosophila melanogaster
Sequence 2:NP_000681.2 Gene:ALDH2 / 217 HGNCID:404 Length:517 Species:Homo sapiens


Alignment Length:96 Identity:22/96 - (22%)
Similarity:38/96 - (39%) Gaps:17/96 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   192 GIRTVFGG--QGPREYILQVLPQLKYLDGL---------PTSRNAAYATLSSSQGQGPDSTSNSE 245
            |.:.:.||  ...|.|.:|........||:         |..:...:.|:....|:..:||..  
Human   381 GAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYG-- 443

  Fly   246 KPPLASAFTFKDIIRPKY-SRKSHSGRMFGN 275
               ||:|...||:.:..| |:...:|.::.|
Human   444 ---LAAAVFTKDLDKANYLSQALQAGTVWVN 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MESK4NP_001262650.1 leucine-rich repeat 111..132 CDD:275378
leucine-rich repeat 133..154 CDD:275378
leucine-rich repeat 155..181 CDD:275378
ALDH2NP_000681.2 ALDH_F1AB_F2_RALDH1 31..511 CDD:143459 22/96 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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