DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MESK4 and alh-10

DIOPT Version :9

Sequence 1:NP_001262650.1 Gene:MESK4 / 64872 FlyBaseID:FBgn0043069 Length:280 Species:Drosophila melanogaster
Sequence 2:NP_509203.1 Gene:alh-10 / 180979 WormBaseID:WBGene00000116 Length:506 Species:Caenorhabditis elegans


Alignment Length:186 Identity:36/186 - (19%)
Similarity:67/186 - (36%) Gaps:42/186 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 TEVLRNCANIQSLESLNYEYND--VLLTEDNVGKMITPNPYSFSGNISISSCPSEDVSFSESILE 84
            |.|.:..|.:..:.:|..|:||  .:|...:.||     |...:..:.|..|......|:.:.| 
 Worm    82 TTVQQRSALLNKVANLIEEFNDDIAILESRDQGK-----PIGLAKVMDIPRCVQNFRDFANAAL- 140

  Fly    85 DNGRISLAYENLKTIPRRLADKFAAQTKFLDLSHNDFRNLRFLSFFEDLDTLILDRNVNLDINTF 149
                .||:...:...|         ..||::...||...:.         .||...|:.|.:.:|
 Worm   141 ----YSLSTSTILEQP---------TGKFVNYVKNDPVGVA---------GLISPWNLPLYLLSF 183

  Fly   150 PYLPSL---RILWINNCDIANITDWIHRIERHCPALDQLSCMG-NPGIRTVFGGQG 201
            ...|:|   ..:.....::.::|.|:        .:.....:| .||:..:..|:|
 Worm   184 KLAPALVAGNTVVCKPSEMTSVTAWV--------LMHAFKLVGFPPGVVNMVIGEG 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MESK4NP_001262650.1 leucine-rich repeat 111..132 CDD:275378 4/20 (20%)
leucine-rich repeat 133..154 CDD:275378 5/20 (25%)
leucine-rich repeat 155..181 CDD:275378 3/28 (11%)
alh-10NP_509203.1 ALDH_F8_HMSADH 45..500 CDD:143412 36/186 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1012
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.