Protein Alignment ISL2 and Bx

DIOPT Version :10

• Sequence 1: NP_665804.1
• Gene: ISL2 / 64843
• HGNCID: 18524
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_001259687.1
• Gene: Bx / 32846
• FlyBaseID: FBgn0265598
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 168
• Identity: 60/168 - (35%)
• Similarity: 88/168 - (52%)
• Gaps: 16/168 - (9%)

Human    13 AMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDET-CTCFVRDGKTY 76
            |..:::....|:.:|.|||..|.|:::|| :.|:.||..||||..|...|.|. .|.:.:.....
  Fly    78 ANNNNNNNNNGSQLCAGCGKHIQDRYLLR-ALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLML 141

Human    77 CKRDYVRLFGIK--CAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLC 139
            |||||:||||..  ||.|.....:.::|||||.:|||:|||.|..|:.:...||.|.|.|:::||
  Fly   142 CKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILC 206

Human   140 R------------ADHGLLLERAAAGSPRSPGPLPGAR 165
            .            |:|.:|....::....||....||:
  Fly   207 EYDYEERLVFASMANHPMLKRHVSSLGQGSPTGAAGAQ 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ISL2	NP_665804.1	LIM1_Isl	27..81	CDD:188752	22/54 (41%)
		LIM2_Isl2	89..143	CDD:188855	24/65 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..191		4/15 (27%)
		HOX	191..247	CDD:197696
		LIM-binding domain (LID). /evidence=ECO:0000250	272..301
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	326..359
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	22/54 (41%)
		LIM2_dLMO	156..210	CDD:188776	23/53 (43%)