DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ELOVL1 and eloF

DIOPT Version :9

Sequence 1:	NP_001243328.1	Gene:	ELOVL1 / 64834	HGNCID:	14418	Length:	279	Species:	Homo sapiens
Sequence 2:	NP_649956.1	Gene:	eloF / 41211	FlyBaseID:	FBgn0037762	Length:	257	Species:	Drosophila melanogaster

Alignment Length:	264	Identity:	92/264 - (34%)
Similarity:	145/264 - (54%)	Gaps:	37/264 - (14%)

- Green bases have known domain annotations that are detailed below.

Human    23 PLMGSPLLMTSILLTYVYFVLSLGPRIMANRKPFQLRG-------FMIVYNFSLVALSLYIVYEF 80
            |::.:|.:....|:.|:.|||.|||:||.:||||.|.|       |.|:||..::.|.::.::.
  Fly    11 PVVSNPWITMGTLIGYLLFVLKLGPKIMEHRKPFHLNGVIRIYNIFQILYNGLILVLGVHFLFV- 74

Human    81 LMSGWLSTYTWRCD---PVDYS-NSPEALRMVRVAWLFLFSKFIELMDTVIFILRKKDGQVTFLH 141
                 |..|...|.   |:|:. ...|.|    :..|:|.:||::|::|:.|:|||||.|::|||
  Fly    75 -----LKAYQISCIVSLPMDHKYKDRERL----ICTLYLVNKFVDLVETIFFVLRKKDRQISFLH 130

Human   142 VFHHSVLP-WSWWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFGPVAQPYLWWKKHMTAIQ 205
            ||||..:. :.:.:......||:.....::|::||||||.||.||:.....|..|||||::|..|
  Fly   131 VFHHFAMAFFGYLYYCFHGYGGVAFPQCLLNTAVHVIMYAYYYLSSISKEVQRSLWWKKYITIAQ 195

Human   206 LIQFVLVSLHISQYYFMSSCNYQYPVIIHLIWMYG-----TIFFMLFSNFWYHSYTK-GKRLPRA 264
            |:||.::.||.:......:|....|:      .||     ..|.::||.|:||:|.| ||   ::
  Fly   196 LVQFAIILLHCTITLAQPNCAVNRPL------TYGCGSLSAFFAVIFSQFYYHNYIKPGK---KS 251

Human   265 LQQN 268
            .:||
  Fly   252 AKQN 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELOVL1	NP_001243328.1	ELO	23..260	CDD:307345	89/254 (35%)
ELOVL1	NP_001243328.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
eloF	NP_649956.1	ELO	11..252	CDD:279492	90/259 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2831
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R389
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.900