DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELOVL1 and CG8534

DIOPT Version :9

Sequence 1:	NP_001243328.1	Gene:	ELOVL1 / 64834	HGNCID:	14418	Length:	279	Species:	Homo sapiens
Sequence 2:	NP_649955.1	Gene:	CG8534 / 41210	FlyBaseID:	FBgn0037761	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	263	Identity:	96/263 - (36%)
Similarity:	142/263 - (53%)	Gaps:	33/263 - (12%)

- Green bases have known domain annotations that are detailed below.

Human    23 PLMGSPLLMTSILLTYVYFVLSLGPRIMANRKPFQLRGFMIVYNFSLVALSLYIVYE--FLMSGW 85
            ||:|||....:|:..|:.|||.||.:.|.||||:.||..:..||.      :.|||.  .|::|.
  Fly    19 PLIGSPWPSLTIVSLYLLFVLKLGRKFMENRKPYDLRRVIRAYNI------MQIVYNGVILIAGL 77

Human    86 -----LSTYTWRCD---PVDYSNSPEALRMVRVAWL---FLFSKFIELMDTVIFILRKKDGQVTF 139
                 |..|..||.   |:|:....      |..||   :.|:||::|::||.|:|||||.|::|
  Fly    78 HFLFVLKAYDLRCITKLPLDHELKS------RERWLTYSYFFNKFMDLLETVFFVLRKKDRQISF 136

Human   140 LHVFHHSVLPWSWWWGVKIAPGGMGSF---HAMINSSVHVIMYLYYGLSAFGPVAQPYLWWKKHM 201
            ||||||.|:.:..:  :.|...|.|..   ..::|.:||||||.||.||:.....|... |||::
  Fly   137 LHVFHHLVMSFGGY--LHITFNGYGGTLFPLCLLNVAVHVIMYAYYYLSSVSKDVQTSR-WKKYI 198

Human   202 TAIQLIQFVLVSLHISQYYFMSSCNYQYPVIIHLIWMYGTIFFMLFSNFWYHSY-TKGKRLPRAL 265
            |.:||:||:||..:.|.......||....||...::: .|.|.::|:||:.|:| ..|.:...||
  Fly   199 TIVQLVQFILVLANFSYTLMQPDCNASRTVIYTGMFI-STTFILMFANFYIHNYILNGSKQKSAL 262

Human   266 QQN 268
            :.:
  Fly   263 KSD 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELOVL1	NP_001243328.1	ELO	23..260	CDD:307345	94/253 (37%)
ELOVL1	NP_001243328.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
CG8534	NP_649955.1	ELO	19..259	CDD:366492	94/255 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920