DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ELOVL1 and CG31523

DIOPT Version :9

Sequence 1:	NP_001243328.1	Gene:	ELOVL1 / 64834	HGNCID:	14418	Length:	279	Species:	Homo sapiens
Sequence 2:	NP_001262255.1	Gene:	CG31523 / 326148	FlyBaseID:	FBgn0051523	Length:	354	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	117/266 - (43%)
Similarity:	168/266 - (63%)	Gaps:	8/266 - (3%)

- Green bases have known domain annotations that are detailed below.

Human     8 YQEVMKH-ADPRIQGYPLMGSPLLMTSILLTYVYFVLSLGPRIMANRKPFQLRGFMIVYNFSLVA 71
            |:::|.: :|||:..:.|:.|||....:.:.|.||..|||||:||.|||.:||..::|||.....
  Fly    12 YRDLMDNKSDPRVNDFFLLSSPLPTLCMCIFYAYFSKSLGPRLMAKRKPMELRSVLVVYNAIQTI 76

Human    72 LSLYIVYEFLMSGWLSTYTWRCDPVDYSNSPEALRMVRVAWLFLFSKFIELMDTVIFILRKKDGQ 136
            .|.:|.||:|||||...|:.:|.|||||.:..|:|||.:.|.:..|||.|..||:.||||||:..
  Fly    77 FSAWIFYEYLMSGWWGHYSLKCQPVDYSTTGLAMRMVNICWWYYISKFTEFFDTLFFILRKKNEH 141

Human   137 VTFLHVFHHSVLPWSWWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFGPVAQPYLWWKKHM 201
            |:.|||.||..:|:|.|.|:|.||||..:|.|::||.||::||.||.::|.||..|.|:||||::
  Fly   142 VSTLHVIHHGCMPFSVWMGLKFAPGGHSTFFALLNSFVHIVMYFYYMIAAMGPKYQKYIWWKKYL 206

Human   202 TAIQLIQFVLVSLHISQYYFMSSCNYQYPVIIHLIW--MYGTIFFMLFSNFWYHSYTKGKRLPR- 263
            |..|::|||.:..|..|..| ..|:|...   .::|  ::|.:|..|||:|:...|....|..|
  Fly   207 TTFQMVQFVAIFTHQFQLLF-RECDYPKG---FMVWIGLHGVMFLFLFSDFYKAKYLNAARRRRQ 267

Human   264 ALQQNG 269
            |::.||
  Fly   268 AVKANG 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELOVL1	NP_001243328.1	ELO	23..260	CDD:307345	107/238 (45%)
ELOVL1	NP_001243328.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
CG31523	NP_001262255.1	ELO	28..265	CDD:279492	108/240 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147555
Domainoid	1	1.000	269	1.000	Domainoid score	I1854
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	280	1.000	Inparanoid score	I2906
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	1	1.000	-	-		mtm8565
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11157
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.860