DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ELOVL1 and Elo68alpha

DIOPT Version :9

Sequence 1:	NP_001243328.1	Gene:	ELOVL1 / 64834	HGNCID:	14418	Length:	279	Species:	Homo sapiens
Sequence 2:	NP_729666.2	Gene:	Elo68alpha / 317841	FlyBaseID:	FBgn0052072	Length:	262	Species:	Drosophila melanogaster

Alignment Length:	245	Identity:	87/245 - (35%)
Similarity:	128/245 - (52%)	Gaps:	11/245 - (4%)

- Green bases have known domain annotations that are detailed below.

Human    16 DPRIQGYPLMGS----PLLMTSILLTYVYFVLSLGPRIMANRKPFQLRGFMIVYNFSLVALSLYI 76
            |.|.:.:||:.|    |:|::..||...|     .|:.....||.|||..:..::.::|.|:.||
  Fly    16 DERTRNWPLVDSFWTVPVLLSIYLLMVRY-----APKWTTRHKPLQLRAPLFCHSLAMVFLNGYI 75

Human    77 VYEFLMSGWLSTYTWRCDPVDYSNSPEALRMVRVAWLFLFSKFIELMDTVIFILRKKDGQVTFLH 141
            ..|...:.....|.:.|.|...|..|..:|:.:..|.|..||.:|..||..||||:|..|::|||
  Fly    76 CLELYAATRDLDYNFGCQPCRVSFDPHEMRLTKAFWWFYISKILEFADTAFFILRQKWSQLSFLH 140

Human   142 VFHHSVLPWSWWWGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSAFGPVAQPYLWWKKHMTAIQL 206
            |:|||.:....|..:|..|.|.....|||||.||:|||.||.||..||..|.:||||:::|.:||
  Fly   141 VYHHSTMFVFCWILIKWMPTGSTYVPAMINSFVHIIMYGYYALSVLGPRVQRFLWWKRYLTGLQL 205

Human   207 IQFVLVSLHISQYYFMSSCNYQYPVIIHLIWMYGTIFFMLFSNFWYHSYT 256
            :||.::....|| ..:..|.|...:.:.:. :|...|..:|..|:...||
  Fly   206 VQFTIIFFWASQ-MLVRGCEYGTWITLSMA-IYSLPFLFMFGKFYMQKYT 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ELOVL1	NP_001243328.1	ELO	23..260	CDD:307345	85/238 (36%)
ELOVL1	NP_001243328.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
Elo68alpha	NP_729666.2	ELO	23..260	CDD:279492	85/238 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820