Protein Alignment BMI1 and Bmi1

DIOPT Version :9

• Sequence 1: NP_005171.4
• Gene: BMI1 / 648
• HGNCID: 1066
• Length: 326
• Species: Homo sapiens
• Sequence 2: NP_001100838.1
• Gene: Bmi1 / 307151
• RGDID: 1307403
• Length: 324
• Species: Rattus norvegicus
• Alignment Length: 326
• Identity: 309/326 - (94%)
• Similarity: 315/326 - (96%)
• Gaps: 2/326 - (0%)

Human     1 MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRP 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRP 65

Human    66 LLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEI 130
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|:|.||||
  Rat    66 LLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDRRVIADDEI 130

Human   131 ISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMY 195
            ||||||||..:|.||||.  |||.|||||||||||||||:|||||||||||||||||||||||||
  Rat   131 ISLSIEFFHPSRSDRKVT--KEKPKEEVNDKRYLRCPAALTVMHLRKFLRSKMDIPNTFQIDVMY 193

Human   196 EEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANS 260
            ||||||||||||||||||||||||||||||||||||||||:|.||||||.|||||||||||||||
  Rat   194 EEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKMSQQRDGLTAAGELESDSGSDKANS 258

Human   261 PAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGSSATSS 325
            ||||.||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||
  Rat   259 PAGGAPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFASRPRKSSVNGSSATSS 323

Human   326 G 326
            |
  Rat   324 G 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BMI1	NP_005171.4	RING-HC_PCGF4	12..65	CDD:319650	52/52 (100%)
		Nuclear localization signal. /evidence=ECO:0000255	81..95		13/13 (100%)
		RAWUL_PCGF4	130..226	CDD:340685	86/95 (91%)
		Interaction with PHC2. /evidence=ECO:0000269|PubMed:27827373	162..182		18/19 (95%)
		Interaction with E4F1. /evidence=ECO:0000269|PubMed:16882984	164..228		62/63 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..326		84/89 (94%)
Bmi1	NP_001100838.1	RING-HC_PCGF4	12..65	CDD:319650	52/52 (100%)
		RAWUL_PCGF4	130..224	CDD:340685	86/95 (91%)
		PRK10803	<222..>279	CDD:182745	52/56 (93%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83683654
Domainoid	1	1.000	196	1.000	Domainoid score	I24722
eggNOG	1	0.900	-	-		E1_KOG2660
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	633	1.000	Inparanoid score	I9713
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG44110
OrthoDB	1	1.010	-	-		D1344247at2759
OrthoFinder	1	1.000	-	-		FOG0000290
OrthoInspector	1	1.000	-	-		oto131523
orthoMCL	1	0.900	-	-		OOG6_107240
Panther	1	1.100	-	-	LDO	PTHR10825
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X10345
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	16.270