DRSC/TRiP Functional Genomics Resources

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Protein Alignment MICAL1 and Rassf

DIOPT Version :10

Sequence 1:NP_001273542.1 Gene:MICAL1 / 64780 HGNCID:20619 Length:1086 Species:Homo sapiens
Sequence 2:NP_651126.3 Gene:Rassf / 42734 FlyBaseID:FBgn0039055 Length:806 Species:Drosophila melanogaster


Alignment Length:352 Identity:70/352 - (19%)
Similarity:114/352 - (32%) Gaps:113/352 - (32%)


- Green bases have known domain annotations that are detailed below.


Human   716 CALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQH---PGDGHFYCLQHLPQTDHKA 777
            |..||:.:|..||....|:.:|..|.||..|...|.||.:.:|   |     ||  |:|     .
  Fly     4 CHKCGKPVYFAERKQSIGYDWHPECLRCEECGKRLNPGQHAEHKSVP-----YC--HVP-----C 56

Human   778 EGSDRGPESPELPTPSENSMP---PGLSTPTASQEGAGPVPDPSQPTR----------RQIRLSS 829
            .|:..||:.....|..|:...   .|...||.:|....|:|.....::          :.:.:.|
  Fly    57 YGALFGPQLFGHGTRVESHKSYGVKGAQKPTGAQANGPPLPRDHLESKLKVYNQFYDNKSLEIRS 121

Human   830 PE-RQRL-------------SSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQA 880
            .| ..||             ..::|..|.:.....:...|| .:::.|.|||             
  Fly   122 REVNNRLVLEGALRVYWGVQGVIHLKEDDDQRILVRKRNSC-RVSKAANESS------------- 172

Human   881 LVAMEKEEKES---PFSSEEEEEDVPLDSDVEQAL------------------------------ 912
             ...|.|..||   |.::..|.:.:..|..:.:::                              
  Fly   173 -SDKENEASESLAPPTTTTAEVDQLSTDVSLSESMTFDSCSLNEISELPTTPEDASANTTANSKE 236

Human   913 ------------QTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQ--------TIQRRLNEI 957
                        .|...:|||:...||...:.:......::.|..|..        .::||.|:.
  Fly   237 QTNGNVCNDDEDTTTTDSSGTLVEAPTASTSCVSSTLPSKLDRLEKLDWDDIDDLLQVERRHNDK 301

Human   958 EAALRELEAEGVKLELALRRQSSSPEQ 984
            :   |..|...|||..:.....|||.:
  Fly   302 D---RIYETMPVKLPSSQSSSDSSPSK 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MICAL1NP_001273542.1 UbiH 102..>218 CDD:440419
CH_MICAL1 526..631 CDD:409045
LIM_Mical_like 716..769 CDD:188744 19/55 (35%)
bMERB_dom 953..1079 CDD:463467 10/32 (31%)
RassfNP_651126.3 LIM_TLP_like 4..57 CDD:188785 21/64 (33%)
RA_RASSF2_like 660..746 CDD:340482
SARAH_RASSF2-like 757..801 CDD:439180
Blue background indicates that the domain is not in the aligned region.

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