Protein Alignment GORASP1 and Grasp65

DIOPT Version :10

• Sequence 1: XP_006713364.1
• Gene: GORASP1 / 64689
• HGNCID: 16769
• Length: 445
• Species: Homo sapiens
• Sequence 2: NP_649160.1
• Gene: Grasp65 / 40177
• FlyBaseID: FBgn0036919
• Length: 460
• Species: Drosophila melanogaster
• Alignment Length: 448
• Identity: 171/448 - (38%)
• Similarity: 235/448 - (52%)
• Gaps: 74/448 - (16%)

Human    26 QVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVV 90
            :||:|||.|:||||.:||||:.|..:||:::||.||.||:.||:|||:|.|::.||..|||:.:.
  Fly    21 KVQDNSPGQKAGLEAFFDFIVAIAGTRLDQDNDMLKELLRQNVDKPVRLTVYSSKTQTVRELTLT 85

Human    91 PSNMWGGQGLLGASVRFCSFRRASEQVWHVLDVEPSSPAALAGLRPYTDYVVGSDQILQESEDFF 155
            |||.||||||||.|:|||||..|:|.|||:|:|.|:|||.|||||.|:|||:|:|.|..|::|.|
  Fly    86 PSNNWGGQGLLGVSIRFCSFEGANESVWHILEVHPNSPAELAGLRAYSDYVIGADAIRHENDDLF 150

Human   156 TLIESHEGKPLKLMVYNSKSDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQ----PPSYHK 216
            ||||:||.:|||:.|||...|:|||||:.||.||||||:||||||:|||||||.|    ..|...
  Fly   151 TLIETHEQQPLKMYVYNLDDDACREVTIKPNTAWGGEGALGCGIGFGYLHRIPVQAEPVTSSSAA 215

Human   217 KPPGTPPPSALPL----GAPPPDA------------LPP-----GPTPED--SPSLETGSRQ--- 255
            .|......|..||    ||.|..|            :||     |.|..:  .|::|..::.
  Fly   216 VPAAAAAESTAPLLTAGGAAPAGAQVAQVVSPTLPYIPPLANTFGSTNAEVRPPTIEPPAQSLFK 280

Human   256 --------SDYMEALLQAPGSSMEDPLPGPGSP-----SHSAPDPDGLPHFMETPLQPPPPVQRV 307
                    :|.:.|.|::. :::.:|:..|..|     |.:.|...     :..|.||.||...:
  Fly   281 TYFNPDEATDALTAALESQ-ATIAEPVSVPAPPAVADVSVAQPQVQ-----VPAPAQPLPPPANI 339

Human   308 MDPGFLDVSGISLLDNSNA-----SVWPSLPSSTELTTTAVSTSGPEDICSSSS---SHERGGEA 364
            ..||..|.   |...|:||     :.....|.:|.........|.|:....|:.   |:..|.:.
  Fly   340 FIPGVFDP---STQQNANALGGIPAAQLPFPQATAAPAAVPMFSAPQQAYMSAPAALSYPAGAQT 401

Human   365 TWSGSEFEVSFLDSPGAQAQADHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPAS 422
            ..|..:.:.|.    |........|   ||..:....:|.       :..||...||:
  Fly   402 VPSYPQVQPSM----GGLFPTQPTP---LPPQMAHVFAPP-------VPPQAGAAPAA 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GORASP1	XP_006713364.1	PDZ_canonical	<26..105	CDD:483948	46/78 (59%)
		GRASP55_65	74..210	CDD:427981	89/135 (66%)
		PHA03264	<199..303	CDD:223029	36/146 (25%)
Grasp65	NP_649160.1	PDZ_canonical	<14..100	CDD:483948	46/78 (59%)
		GRASP55_65	69..205	CDD:427981	89/135 (66%)