DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SHBG and CG5250

DIOPT Version :9

Sequence 1:NP_001031.2 Gene:SHBG / 6462 HGNCID:10839 Length:402 Species:Homo sapiens
Sequence 2:NP_650793.1 Gene:CG5250 / 42308 FlyBaseID:FBgn0038691 Length:311 Species:Drosophila melanogaster


Alignment Length:137 Identity:32/137 - (23%)
Similarity:51/137 - (37%) Gaps:38/137 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    63 LTKITKTSSSFEVRTWD-----PEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGP 122
            |.|||: :..|:..|:|     ||    |......|  :::||..   |.:.:..|....| ..|
  Fly   156 LIKITQ-ALGFQAVTYDDALTLPE----YAPDELFD--YVVGLGS---EERFNRIWVSCQV-IEP 209

Human   123 RLD------DGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPASN 181
            |:|      ..|:...|......:|.|....::       .|| |.|..|.:|..:        :
  Fly   210 RVDIQFDYHPVRFFDAEELFTSGNVFLNESSDD-------DGP-TYKEDPRLRRII--------S 258

Human   182 LRLPLVP 188
            :||..:|
  Fly   259 VRLSNIP 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SHBGNP_001031.2 Laminin_G_1 75..205 CDD:278483 27/125 (22%)
CG5250NP_650793.1 Na_K-ATPase <143..281 CDD:298651 32/137 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3927
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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