DRSC/TRiP Functional Genomics Resources

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Protein Alignment SHBG and nrv2

DIOPT Version :9

Sequence 1:NP_001031.2 Gene:SHBG / 6462 HGNCID:10839 Length:402 Species:Homo sapiens
Sequence 2:NP_001014475.1 Gene:nrv2 / 33953 FlyBaseID:FBgn0015777 Length:323 Species:Drosophila melanogaster


Alignment Length:146 Identity:34/146 - (23%)
Similarity:52/146 - (35%) Gaps:38/146 - (26%)


- Green bases have known domain annotations that are detailed below.


Human   246 EPWAFSLDLGLKQAAGSGHLLALGT-----------PENPSWLSLHLQDQKVVLSSGSGPGL--- 296
            :.||   .:|:...|..|.|.||..           |..|.|    ..|:.::   |:.|||   
  Fly    46 DSWA---KIGIFYVAFYGVLAALVAICMWAFFQTLDPRIPKW----TLDRSLI---GTNPGLGFR 100

Human   297 DLPLVLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTSF 361
            .||.|..:.       |.::..:|::.:........|...|.::..|      |..||...:...
  Fly   101 PLPPVDNVE-------STLIWYKGTQHENYKHWTDSLDDFLAVYKVP------GLTPGRGQNIYN 152

Human   362 C-LNGLWAQGQRLDVD 376
            | .|....:||..|||
  Fly   153 CDYNQPPPKGQVCDVD 168

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SHBGNP_001031.2 Laminin_G_1 75..205 CDD:278483
nrv2NP_001014475.1 Na_K-ATPase 24..317 CDD:278704 34/146 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3927
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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