Protein Alignment SH3GL2 and sh3gl2b

DIOPT Version :10

• Sequence 1: XP_011516307.1
• Gene: SH3GL2 / 6456
• HGNCID: 10831
• Length: 386
• Species: Homo sapiens
• Sequence 2: NP_001340906.1
• Gene: sh3gl2b / 794400
• ZFINID: ZDB-GENE-170303-2
• Length: 349
• Species: Danio rerio
• Alignment Length: 337
• Identity: 258/337 - (76%)
• Similarity: 300/337 - (89%)
• Gaps: 3/337 - (0%)

Human    50 KVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMINTMSKIRGQ 114
            ||||||||||||||||||||||:|||.|||||::|||||.|||||||||||:|||||||||||||
Zfish    16 KVSEKVGGAEGTKLDDDFKEMEKKVDTTSRAVLDIMTKTTEYLQPNPASRARLSMINTMSKIRGQ 80

Human   115 EKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQN 179
            :|||||||||.:|.:||||||||||::.:||.||.:.||:||||.||||:|||.|||||||||||
Zfish    81 DKGPGYPQAETVLGDAMLKFGRELGEESSFGLALLDAGESMRELGEVKDALDITVKQNFIDPLQN 145

Human   180 LHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIE 244
            ||||||:||||||||:||||||||||||||||:.|:|::||||||||||||||.|||||||.|||
Zfish   146 LHDKDLKEIQHHLKKMEGRRLDFDYKKKRQGKVTDDEIKQALEKFDESKEIAEQSMFNLLENDIE 210

Human   245 QVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNG 309
            |||||:||||||:|||:||.:||||::.::|:|:::.|.:||:|:.|||||.|:.|.   ...||
Zfish   211 QVSQLAALVQAQVEYHQQAAEILQQLSSKIEDRVKEMSDKPRKEFIPKPRMELQLPI---ETLNG 272

Human   310 GLSHTGTPKPSGVQMDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFP 374
            |::...:|..|...:||||||||||||||||||||||||||||||||||:||||||:||.|||||
Zfish   273 GINSAKSPARSPAPLDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDDNWYEGMIHGQSGFFP 337

Human   375 INYVEILVALPH 386
            ||||:|||.|||
Zfish   338 INYVDILVPLPH 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3GL2	XP_011516307.1	BAR_Endophilin_A1	59..281	CDD:153297	176/221 (80%)
		SH3_Endophilin_A	327..381	CDD:212737	49/53 (92%)
sh3gl2b	NP_001340906.1	BAR_Endophilin_A1	25..246	CDD:153297	176/220 (80%)
		SH3_Endophilin_A	290..344	CDD:212737	49/53 (92%)