Protein Alignment SH3GL2 and sh3gl2a

DIOPT Version :10

• Sequence 1: XP_011516307.1
• Gene: SH3GL2 / 6456
• HGNCID: 10831
• Length: 386
• Species: Homo sapiens
• Sequence 2: NP_957410.1
• Gene: sh3gl2a / 394091
• ZFINID: ZDB-GENE-040121-3
• Length: 347
• Species: Danio rerio
• Alignment Length: 337
• Identity: 249/337 - (73%)
• Similarity: 295/337 - (87%)
• Gaps: 5/337 - (1%)

Human    50 KVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMINTMSKIRGQ 114
            :||||||||||||||.||.|||:|||.|||||::|:|||.||||||||:|||:||:::||||||.
Zfish    16 RVSEKVGGAEGTKLDVDFTEMEKKVDTTSRAVLDILTKTTEYLQPNPATRAKMSMMSSMSKIRGG 80

Human   115 EKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQN 179
            :|||||.|.|..|.|||.|.|||||::..||.||.:||||||||.||||:||:||||||||||||
Zfish    81 DKGPGYTQTETTLGEAMQKAGRELGEESCFGVALIDVGEAMRELGEVKDALDMEVKQNFIDPLQN 145

Human   180 LHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIE 244
            :|||||:|||||||||||||||||||||||||:.::|::|||||||:||||||.|||||||.|||
Zfish   146 IHDKDLKEIQHHLKKLEGRRLDFDYKKKRQGKVTEDEIKQALEKFDDSKEIAEQSMFNLLENDIE 210

Human   245 QVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNG 309
            ||||||||||||:.||:||.:||||::.::|:|||:||.:|:|||.||||.||:|    |...||
Zfish   211 QVSQLSALVQAQVNYHRQAAEILQQLSSKIEDRIREASCKPKREYVPKPRTSLDF----SENHNG 271

Human   310 GLSHTGTPKPSGVQMDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFP 374
            .:.|:| |..|...||||||||||||:||||||||||||||||||::||:||||||::|.|||||
Zfish   272 SIGHSG-PSRSPAPMDQPCCRALYDFDPENEGELGFKEGDIITLTSKIDDNWYEGMVNGQSGFFP 335

Human   375 INYVEILVALPH 386
            :|||:|||||||
Zfish   336 VNYVDILVALPH 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3GL2	XP_011516307.1	BAR_Endophilin_A1	59..281	CDD:153297	167/221 (76%)
		SH3_Endophilin_A	327..381	CDD:212737	44/53 (83%)
sh3gl2a	NP_957410.1	BAR_Endophilin_A1	25..247	CDD:153297	167/221 (76%)
		SH3_Endophilin_A	288..342	CDD:212737	44/53 (83%)