Protein Alignment SH3GL2 and sh3gl2

DIOPT Version :10

• Sequence 1: XP_011516307.1
• Gene: SH3GL2 / 6456
• HGNCID: 10831
• Length: 386
• Species: Homo sapiens
• Sequence 2: NP_001090766.1
• Gene: sh3gl2 / 100037852
• XenbaseID: XB-GENE-1012090
• Length: 349
• Species: Xenopus tropicalis
• Alignment Length: 337
• Identity: 294/337 - (87%)
• Similarity: 316/337 - (93%)
• Gaps: 3/337 - (0%)

Human    50 KVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMINTMSKIRGQ 114
            |||||||||||||||:|||||||||||||||||||||||.|||||||||||||||:|||||||||
 Frog    16 KVSEKVGGAEGTKLDEDFKEMERKVDVTSRAVMEIMTKTTEYLQPNPASRAKLSMLNTMSKIRGQ 80

Human   115 EKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQN 179
            |||||||||||||||||.|||||:||:.|||.||.:||:||||||::||.|||:|||||||||||
 Frog    81 EKGPGYPQAEALLAEAMFKFGREIGDESNFGLALIDVGDAMRELSDIKDCLDIDVKQNFIDPLQN 145

Human   180 LHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIE 244
            |||||||||||||||||||||||||||||||||.|:|:|||||||||||||||||||||||||||
 Frog   146 LHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKITDDEIRQALEKFDESKEIAESSMFNLLEMDIE 210

Human   245 QVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNG 309
            ||||||||.|||||||:||.||||||.|:||:|||:||||||||||||||||||.   :::|.||
 Frog   211 QVSQLSALAQAQLEYHRQASQILQQVAVKLEQRIREASSQPRREYQPKPRMSLEL---ENSQLNG 272

Human   310 GLSHTGTPKPSGVQMDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFP 374
            |::..|||||||..||||||||||||:||||||||||||||||||||||||||||||||.|||||
 Frog   273 GIALAGTPKPSGAPMDQPCCRALYDFDPENEGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFP 337

Human   375 INYVEILVALPH 386
            ||||:|||.|||
 Frog   338 INYVDILVPLPH 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3GL2	XP_011516307.1	BAR_Endophilin_A1	59..281	CDD:153297	197/221 (89%)
		SH3_Endophilin_A	327..381	CDD:212737	50/53 (94%)
sh3gl2	NP_001090766.1	BAR_Endophilin_A1	25..247	CDD:153297	197/221 (89%)
		SH3_Endophilin_A	290..344	CDD:212737	50/53 (94%)