Protein Alignment TEKT3 and CG17450

DIOPT Version :10

• Sequence 1: NP_114104.1
• Gene: TEKT3 / 64518
• HGNCID: 14293
• Length: 490
• Species: Homo sapiens
• Sequence 2: NP_728438.2
• Gene: CG17450 / 49952
• FlyBaseID: FBgn0040028
• Length: 601
• Species: Drosophila melanogaster
• Alignment Length: 502
• Identity: 182/502 - (36%)
• Similarity: 291/502 - (57%)
• Gaps: 52/502 - (10%)

Human    31 SSYRDRFPHSNLTHS-------------------------------LSLPWRPSTYYKV--ASNS 62
            :.|.:|..|.||..|                               ...||||:..|::  ..:.
  Fly    94 NEYNERKDHRNLMESYPWSQAGAPPCMEPVMGPSIPPRVGAAYETPTKHPWRPAMAYELIQVKHM 158

Human    63 P------SVAPYCTRSQRVSENTML-----------PFVSNRTTFFTRYTPDDWYRSNLTNYQES 110
            |      .:...|...:.:..:.|:           |..:.|...:||||.::||.:|:|.|.||
  Fly   159 PEQPVTNQLTKQCFLPKGMKTDGMIFPNLVTGFDRNPQHAARAALYTRYTSNEWYNNNMTKYSES 223

Human   111 NTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALT 175
            |.:|:.||::|.|..||:::..::....|.|..:.||||:.|:.||::|:..||:::|.|.:.:.
  Fly   224 NMNRNLSERMRNDAVRLMRETDEKATSGQRDAGRRLGERITDLTFWRNELNAELEKLIAEMSDIN 288

Human   176 DVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERM-KLHLDK 239
            :::::..:||::.|.||.:|:|||||||.|.|.:.|||.||..||.|::.:...::|: .|| :|
  Fly   289 ELQRQCGKALLDLEIPLHIAQECLFHRESRQGTEKVHDIVEKALLVEINNLRNSRDRLGGLH-EK 352

Human   240 AIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFT 304
            ...|....|.:||.||.|:|.|:::..||..||.|.|.|.|:.|:.|:|:.|.:||..||||:.:
  Fly   353 ISKQALDCRGAQHLLEDDVSHKESSLGIDSMCHQLNNHSRGITYYGGIEKFDPSVSTQESWAQAS 417

Human   305 DDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTL 369
            .:::.|||:|||..::||.|.::::...|..:|:.::..|.:|..|..|.|:|||::|.||.|..
  Fly   418 SEHVRRSQAERAKLSQLRSDAQSVVNSVATTVWDFWSNTNNAFDRRSQEMAEAKNRVQLHLQKVQ 482

Human   370 QEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTL 434
            ||:|..|..:..::|||:||:..||||||||:.|:.|..:|||:|.||.|||.||.::...::||
  Fly   483 QELFDMEKHLFLLQKAIQDKSGPLKVAQTRLEARSHREGVELCKDHAQDRLVQEVQDIQGAVETL 547

Human   435 QQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMRKSYP 481
            ..:|.:||.|.|.|:..:.|||.||..|.|:|:||:|||||:|:|:|
  Fly   548 HHKLMEAEATHQGLLKTRCTLEVDLRNKVNALFIDREKCMSLRRSFP 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TEKT3	NP_114104.1	Tektin	99..481	CDD:460827	161/382 (42%)
CG17450	NP_728438.2	Tektin	212..594	CDD:460827	161/382 (42%)