Protein Alignment SH3BGR and Sh3beta

DIOPT Version :10

• Sequence 1: NP_031367.2
• Gene: SH3BGR / 6450
• HGNCID: 10822
• Length: 176
• Species: Homo sapiens
• Sequence 2: NP_001189057.1
• Gene: Sh3beta / 38820
• FlyBaseID: FBgn0035772
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 191
• Identity: 66/191 - (34%)
• Similarity: 105/191 - (54%)
• Gaps: 28/191 - (14%)

Human     1 MVIKVFVATSSGSIAIRKKQQEVVGFLEANKIDFKELDIA--GDEDNRRWMRENVPGEKKPQNG- 62
            ||:||:|:..||:..::|:||.|:..|::..|.:..:||.  |.|..:..|:     .|...||
  Fly     1 MVLKVYVSGMSGNKEVKKRQQRVLMILDSKNIKYDTVDITEPGKESEKELMQ-----NKSTSNGG 60

Human    63 --------IPLPPQIFNEEQYCGDFDSFFSAKEENIIYSFLGLAPPPDSKGS----EKAEEGGET 115
                    .|||||:||:::||||:|:|..|.|.:.:..||.|||...:..|    |..:|.|
  Fly    61 TVSDPEPRHPLPPQLFNDDEYCGDYDAFDMANEIDTLEVFLKLAPADTTAVSTAQIELKQENG-- 123

Human   116 EAQKEGSEDVGNLPEAQEKNEEEGETATEETEEIAMEGAEGEAEEEEETAEGEEPGEDEDS 176
            :|:||.:|     .||::|..|.|:...:..|| |.|.||.|..:::|.::||:...||::
  Fly   124 DAKKEEAE-----TEAEDKKTEAGDGDVDVKEE-AAEKAENEDGKDKENSKGEDEDADEEN 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SH3BGR	NP_031367.2	SH3BGR	1..98	CDD:398530	38/107 (36%)
Sh3beta	NP_001189057.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	1..104	CDD:469754	38/107 (36%)
		2A1904	<138..392	CDD:273344	14/42 (33%)