Protein Alignment SGSH and sgsh

DIOPT Version :10

• Sequence 1: NP_000190.1
• Gene: SGSH / 6448
• HGNCID: 10818
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_001116740.1
• Gene: sgsh / 563849
• ZFINID: ZDB-GENE-030131-4958
• Length: 511
• Species: Danio rerio
• Alignment Length: 503
• Identity: 354/503 - (70%)
• Similarity: 417/503 - (82%)
• Gaps: 10/503 - (1%)

Human     8 CCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSP 72
            |..|...:|.||:  ||.||::|||||||:..|||:.:.||||.||::|||:|:|||||||||||
Zfish    11 CLLLCFDVGGCRS--RNVLLIIADDGGFETDVYNNTVVQTPHLRALSKRSLIFKNAFTSVSSCSP 73

Human    73 SRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFA 137
            ||:::||||||||||||||||.||||||||.|:||||||.:|.:.|||||||||||..|||||||
Zfish    74 SRSTILTGLPQHQNGMYGLHQGVHHFNSFDGVQSLPLLLKRANIHTGIIGKKHVGPGPVYPFDFA 138

Human   138 YTEENGSVLQVGRNITRIKLLVRKFLQ--------TQDDRPFFLYVAFHDPHRCGHSQPQYGTFC 194
            ||||..||||||||||:||||||||.|        |:::|||||||||||||||||||||||.||
Zfish   139 YTEETNSVLQVGRNITKIKLLVRKFFQSHKEERSETKEERPFFLYVAFHDPHRCGHSQPQYGVFC 203

Human   195 EKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRD 259
            ||||||||||||||||.|:.|.|..|.||||:|:|||||||:|||||||.|:|||:||||:|||.
Zfish   204 EKFGNGESGMGRIPDWEPKYYSPDQVKVPYFIPDTPAARADIAAQYTTVSRLDQGIGLVLEELRK 268

Human   260 AGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILD 324
            ||..||||||::||||||||:||||||..|..||:|:|||||.:|||::|:|||||||:||||||
Zfish   269 AGFENDTLVIYSSDNGIPFPNGRTNLYGSGVKEPMLLSSPEHQQRWGKLSQAYVSLLDITPTILD 333

Human   325 WFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHN 389
            |||:|||||::..|:.:.||||||||||.:||.|.|||.|||.|||||.|||||:....:||:||
Zfish   334 WFSLPYPSYSLSMSQPVELTGRSLLPALISEPSWDTVFSSQSLHEVTMFYPMRSIHKGPYRLLHN 398

Human   390 LNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATD 454
            |:::||||||||||:|||||||||||.:|:||||:|.|..||||.||||:|...||.|..|||.|
Zfish   399 LHYRMPFPIDQDFYISPTFQDLLNRTQSGRPTGWFKTLNEYYYRQRWELFDVRTDPMEKVNLAGD 463

Human   455 PRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNEL 502
            ..::::||.|:|.|.||||.|.|||||.||.|||.||.|:|:||:|.|
Zfish   464 LDYSEVLESLKDLLLKWQWRTEDPWVCEPDAVLEAKLEPECRPLYNGL 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SGSH	NP_000190.1	SGSH	24..472	CDD:293751	326/455 (72%)
sgsh	NP_001116740.1	SGSH	25..481	CDD:293751	326/455 (72%)