Protein Alignment SGSH and Sgsh

DIOPT Version :9

• Sequence 1: NP_000190.1
• Gene: SGSH / 6448
• HGNCID: 10818
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_650760.1
• Gene: Sgsh / 42266
• FlyBaseID: FBgn0038660
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 275/503 - (54%)
• Similarity: 338/503 - (67%)
• Gaps: 20/503 - (3%)

Human    11 LLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRA 75
            |.|:.| |.|.|:|.|||||||.|||||||.|....||:|||||:|.|||.|||||||||||||:
  Fly    10 LWLIAG-CSAGPQNVLLLLADDAGFESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSPSRS 73

Human    76 SLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLP-LLLSQAGVR--TGIIGKKHVGPETVYPFDFA 137
            .||||...|.:|||||||.||:||......||| |:..|:|.|  :|||||||||....:.|||.
  Fly    74 QLLTGQAGHSSGMYGLHQGVHNFNVLPDTGSLPNLIRDQSGGRILSGIIGKKHVGAANNFRFDFE 138

Human   138 YTEENGSVLQVGRNITRIKLLVRKFL-QTQDD-RPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNG 200
            .|||..|:.|:||||||:|...|:|| |.:|: :||||.|.|||||||||..||:|.|||::|:|
  Fly   139 QTEEQHSINQIGRNITRMKEYARQFLKQAKDEKKPFFLMVGFHDPHRCGHITPQFGEFCERWGSG 203

Human   201 ESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLND 265
            |.|||.||||.|..||..::.||.::|:|...|.:|||||.|:.|:||||||:|:||..|||.:.
  Fly   204 EEGMGSIPDWKPIYYDWRNLDVPAWLPDTDVVRQELAAQYMTISRLDQGVGLMLKELEAAGVADQ 268

Human   266 TLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPY 330
            ||||:|||||.|||.||||||..|...||::|||....|..:.:.|.|||||:.|:::|...||.
  Fly   269 TLVIYTSDNGPPFPGGRTNLYEHGIRSPLIISSPNKEDRHHEATAAMVSLLDIYPSVMDALQIPR 333

Human   331 PSYAIFGSKTIHLTGRSLLPALEAEPLWA---TVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNF 392
            |:       ...:.|||:||.|..||...   :||||.|:|||||:||||.|::|.::|:||:|:
  Fly   334 PN-------DTKIVGRSILPVLREEPPIKESDSVFGSHSYHEVTMAYPMRMVRNRRYKLIHNINY 391

Human   393 KMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRF 457
            ...||||||||.|||||.:||.|...|...||:.|..||.|..|||||...||.|..|||...::
  Fly   392 WADFPIDQDFYTSPTFQQILNATLRKQTLPWYRSLLQYYQRPEWELYDIKTDPLERFNLADKAKY 456

Human   458 AQLLEMLRDQLAKWQWETHDPWVCAPDGVLEE----KLSPQCQPLHNE 501
            ...|:.||:||..||..|.|||.|||..||:|    |..|.|..|.:|
  Fly   457 NGTLKQLREQLFDWQVATKDPWRCAPHAVLQEQGVYKDQPVCLTLGHE 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SGSH	NP_000190.1	SGSH	24..472	CDD:293751	252/455 (55%)
Sgsh	NP_650760.1	AslA	17..476	CDD:225661	257/465 (55%)
		SGSH	22..471	CDD:293751	252/455 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150913
Domainoid	1	1.000	354	1.000	Domainoid score	I997
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H167
Inparanoid	1	1.050	522	1.000	Inparanoid score	I1266
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63124
OrthoDB	1	1.010	-	-		D194238at33208
OrthoFinder	1	1.000	-	-		FOG0007960
OrthoInspector	1	1.000	-	-		oto89500
orthoMCL	1	0.900	-	-		OOG6_107938
Panther	1	1.100	-	-	LDO	PTHR43108
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5386
SonicParanoid	1	1.000	-	-		X5904
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800