Protein Alignment SGSH and CG7402

DIOPT Version :9

• Sequence 1: NP_000190.1
• Gene: SGSH / 6448
• HGNCID: 10818
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_649023.1
• Gene: CG7402 / 39994
• FlyBaseID: FBgn0036768
• Length: 579
• Species: Drosophila melanogaster
• Alignment Length: 575
• Identity: 130/575 - (22%)
• Similarity: 210/575 - (36%)
• Gaps: 156/575 - (27%)

Human    11 LLLVLGLCRARPRNALLLLADDGGFESGAYNNS-AIATPHLDALARRSLLFRNAFTSVSSCSPSR 74
            |.|..|...:...|.:::|.||.|....:::.| .|.||::||||...:|....:.. :.|:|||
  Fly    16 LSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVP-NLCTPSR 79

Human    75 ASLLTGLPQHQNGMYGLHQDVHHFNSF--------DKVRSLPLLLSQAGVRTGIIGKKHVG---- 127
            |:|||       |.|.:|..:.||...        .:.|.:|.:...||..|.::||.|:|
  Fly    80 ATLLT-------GKYPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRK 137

Human   128 --PETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQY 190
              ..|:..||..:...||.:.....   ::::|.|.:....|.|        .|...|..:...|
  Fly   138 DLTPTMRGFDHHFGYYNGYIDYYDH---QVRMLDRNYSAGLDFR--------RDLEPCPEANGTY 191

Human   191 GTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNT-----------------PAARADLAA 238
            .|  |.|   .|...||.:...:: .||.:::.:...:|                 |..|.....
  Fly   192 AT--EAF---TSEAKRIIEQHDKS-KPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRR 250

Human   239 QYT-TVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIP-----------FP-SGRTNLYWPGT 290
            .|. .:..:|:.|...:..|:|.|:||:::::..||||.|           :| .|:....|.|.
  Fly   251 TYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKESPWEGG 315

Human   291 A-------EPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSL 348
            .       .|||       |..|.||...:..:|..||:.....:..|       :.:.|.|.:|
  Fly   316 IRSAGALWSPLL-------KERGYVSNQAIHAVDWLPTLAGAAGVSLP-------QDLPLDGINL 366

Human   349 LPALEA--EPLWAT-------VFGSQSHHEVTMSYPM-RSVQHRHFRLVHNLNFKMPFPIDQDF- 402
            .|.|..  ||...|       |||..|:...|:.|.. .|.:.|:.:.:..|......|:.:.:
  Fly   367 WPMLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYE 431

Human   403 --YVSPTFQDLL-NR--------------TTAGQPTGWYKDLRHYYYRARWE------LYDRSRD 444
              .::...|.|| ||              |....|......|..::   :.|      .:|.::|
  Fly   432 QHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQNPLESHF---KCEPLKAPCFFDLAKD 493

Human   445 PHETQNLATDPRFAQLLEMLRDQL--------------------------AKWQW 473
            |.|..|||  ..:...|:.|.|:|                          ..|:|
  Fly   494 PCERYNLA--QMYPLQLQQLADELEQIRKTAIPSARVPHSDSRANPTFHNGNWEW 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SGSH	NP_000190.1	SGSH	24..472	CDD:293751	125/559 (22%)
CG7402	NP_649023.1	PRK13759	25..459	CDD:237491	110/472 (23%)
		4-S	28..436	CDD:293753	105/446 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810