Protein Alignment SGSH and sgsh

DIOPT Version :10

• Sequence 1: NP_000190.1
• Gene: SGSH / 6448
• HGNCID: 10818
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_001120065.1
• Gene: sgsh / 100145064
• XenbaseID: XB-GENE-1005174
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 364/493 - (73%)
• Similarity: 425/493 - (86%)
• Gaps: 4/493 - (0%)

Human    10 ALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSR 74
            :|||   |.:|..||.||::.||.||||..|||:||.||:|..|::|||:|:|||||||||||||
 Frog    15 SLLL---LSKAWGRNVLLIIGDDAGFESEVYNNTAIHTPNLRDLSKRSLIFKNAFTSVSSCSPSR 76

Human    75 ASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYT 139
            |:::||||||||||||||||:|||||||.||||||:|.|||:|||||||||:|||:||||||:||
 Frog    77 AAIMTGLPQHQNGMYGLHQDMHHFNSFDDVRSLPLILRQAGIRTGIIGKKHIGPESVYPFDFSYT 141

Human   140 EENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGM 204
            |||.|||||||||||||||||||||:||.|||.|||||||||||||||||||.||||||||:..|
 Frog   142 EENSSVLQVGRNITRIKLLVRKFLQSQDQRPFLLYVAFHDPHRCGHSQPQYGAFCEKFGNGDPDM 206

Human   205 GRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVI 269
            |.:|||:||.|.|..|.||||:.:||:||.|:||||||:||||||:||||.||.:||..||||||
 Frog   207 GIMPDWSPQYYTPEQVQVPYFIQDTPSARKDIAAQYTTIGRMDQGIGLVLSELYNAGHENDTLVI 271

Human   270 FTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYA 334
            |:||||||||:|||||||.|.|||||||||.|.|||||:|:::.||||:|||:|||||||||:|.
 Frog   272 FSSDNGIPFPNGRTNLYWSGRAEPLLVSSPYHQKRWGQISQSFASLLDITPTVLDWFSIPYPNYK 336

Human   335 IFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPID 399
            ||| |::.|||:||||||::|..|.|||||||||||||.|||||||:..:.|:||||||||||||
 Frog   337 IFG-KSVQLTGKSLLPALQSEQDWTTVFGSQSHHEVTMYYPMRSVQNLQYLLIHNLNFKMPFPID 400

Human   400 QDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEML 464
            ||||||||||||||||.:||||.|:|.|.:||||.||||||||.|..|.:|:|.||.:..:|:.:
 Frog   401 QDFYVSPTFQDLLNRTVSGQPTSWFKTLHNYYYRDRWELYDRSADISEIKNIAEDPAYQDILKSM 465

Human   465 RDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNEL 502
            ::.|.|||.||.|||:|||||||||||.|||:||:|||
 Frog   466 QNILQKWQSETSDPWMCAPDGVLEEKLEPQCRPLYNEL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SGSH	NP_000190.1	SGSH	24..472	CDD:293751	332/447 (74%)
sgsh	NP_001120065.1	SGSH	26..473	CDD:293751	332/447 (74%)