Protein Alignment SGK1 and sgk-1

DIOPT Version :9

• Sequence 1: NP_001137148.1
• Gene: SGK1 / 6446
• HGNCID: 10810
• Length: 526
• Species: Homo sapiens
• Sequence 2: NP_001041299.1
• Gene: sgk-1 / 181697
• WormBaseID: WBGene00004789
• Length: 463
• Species: Caenorhabditis elegans
• Alignment Length: 402
• Identity: 207/402 - (51%)
• Similarity: 278/402 - (69%)
• Gaps: 20/402 - (4%)

Human   103 ANILTKPDPRTFWTNDDPAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKISQPQEPELMNAN 167
            |.|.|.|..:  :...|..|.::||:.:....|.:.:|:  .:..:|:....:..|.:.|
 Worm    62 ATIFTAPKKK--FLQADSKFYEKRRVWILVISQHLVDNN--LRSEDVRRFFHLESPDDDE----- 117

Human   168 PSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKK 232
                    ..::||||....|..:||.:|..|||||||:|...|||..:..||:|:|.|:.|.||
 Worm   118 --------NNVDLGPSERKTATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKK 174

Human   233 KEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFY 297
            .|.||:|:|||||:.|.||||||.||||||..:|||||||::||||||.|||||:.|.|.|:|||
 Worm   175 NEVKHVMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFY 239

Human   298 AAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPE 362
            |||||.||||||..||:||||||||:|||.:|::||||||||||:::.:.|||||||||||||||
 Worm   240 AAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAPE 304

Human   363 VLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLL 427
            ::.|:|||:||||||||:|||||::|||||||::..||||.|:|:||:||.||:.....|:.|||
 Worm   305 IILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSELITGLL 369

Human   428 QKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPV-PN 491
            ||||:||||.::||.:|:.|.||..::||.|:|:::..||.|.|....|..:...||.|..: |:
 Worm   370 QKDRSKRLGHRNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNISKEFVEIQIDPS 434

Human   492 SIGKSPDSVLVT 503
            |:  :|..:.||
 Worm   435 SL--APQQLAVT 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SGK1	NP_001137148.1	S_TKc	193..450	CDD:214567	169/256 (66%)
		STKc_SGK	197..519	CDD:270727	186/308 (60%)
sgk-1	NP_001041299.1	S_TKc	135..392	CDD:214567	169/256 (66%)
		STKc_SGK	139..456	CDD:270727	186/308 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	370	1.000	Domainoid score	I505
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H48364
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1159
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D196627at33208
OrthoFinder	1	1.000	-	-		FOG0001348
OrthoInspector	1	1.000	-	-		otm15346
orthoMCL	1	0.900	-	-		OOG6_100157
Panther	1	1.100	-	-	O	PTHR24356
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R469
SonicParanoid	1	1.000	-	-		X760
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.000