Protein Alignment Slc5a4b and CG33124

DIOPT Version :9

• Sequence 1: NP_075708.2
• Gene: Slc5a4b / 64454
• MGIID: 1890478
• Length: 660
• Species: Mus musculus
• Sequence 2: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 135/642 - (21%)
• Similarity: 256/642 - (39%)
• Gaps: 163/642 - (25%)

Mouse    28 DISVIVIYFIVVLAVGLW---------SMVRSNRGT------------VGGFFLAGHDMAWWPMG 71
            |.:|.:...|:.:|:||:         .|..|...|            :..:.:....:..:|:.
  Fly    10 DYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPVA 74

Mouse    72 ASLFASNIGSNHFVGLAGTGAASGIAIAAVEWNALLMVLVL-----GWVFLPIYIKAGVLTMPEY 131
            .||.||.|.     |:|..|..|.|.....:::.:::.:|:     .:::||::....|.:..||
  Fly    75 MSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEY 134

Mouse   132 LRKRFGGKRLQIYLSVLSLF--IMVALQTSSIIFSGAIFIQLALGLNLYLAVFILLAITAFYTVA 194
            |..||.    .:..:::|:.  |.|.|.|..::|..|:.:..|.|||:::...:::.:...||:.
  Fly   135 LGMRFH----PLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLL 195

Mouse   195 GGLASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAIPSVVEGDNL---TISPKCY 256
            |||.:|::||..|..||....:::...|...:...:.|.|       |:|:|..|   .|:|..|
  Fly   196 GGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFE-------SLVDGGRLIFGNINPSPY 253

Mouse   257 TPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYW----CADQVIVQRCLCGKN--MSHVKAACI 315
            .         |:.|     |..:|.|     .:||    ...|.:|.|.:...|  |:....|..
  Fly   254 V---------RNTV-----WSVVIGG-----AFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFF 299

Mouse   316 LCGYLKLLPMFLMVMP--GMISRILYTDKVACVVPSECEKQCGTAVGCTNYAYPTLVLELMPD-- 376
            :.|.:    :|..|:.  |::...:|.|         |:......:...:...|..|::.:..
  Fly   300 VLGSI----IFYSVLSFLGLLIFNMYKD---------CDPLSAGQIMNNDQLVPLFVVQSVGHIY 351

Mouse   377 GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLY------------TKIRKKASERELMIAGR-I 428
            |:.||.::.:..:.:|||:...||.|.:...|:.            :.|..||:   ::|.|. :
  Fly   352 GIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKAT---IVIMGALV 413

Mouse   429 FGMVLIAVSI-----LWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFFKRVNEQGAFWG 488
            ||.||:...:     :.:.||.:           :.||..|     :|.||:.....|..|...|
  Fly   414 FGEVLLLEKVSGILSICMSLVAI-----------ATSSTFG-----IFTLAVLVPWANTVGTAVG 462

Mouse   489 LMVG-LVVGLIRLIAEFVYGTGSC------VAPSNCPKIICGVHYMY---------FAIILFFVS 537
            .:.| |:.|.|...::....:|..      |:.::||..:.....::         |.:...:::
  Fly   463 GIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHWIN 527

Mouse   538 -----IIVILG--VSFLTEPI-----------PDVH--LYRLCWSLWN-NTEERIDL 573
                 .:|::|  ||.:|:|.           |.:|  |.:.|:...| :..|..|:
  Fly   528 PIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDKSEATDI 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a4b	NP_075708.2	SLC5-6-like_sbd	27..660	CDD:294310	135/642 (21%)
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	122/589 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750