Protein Alignment Slc5a4b and CG31262

DIOPT Version :9

• Sequence 1: NP_075708.2
• Gene: Slc5a4b / 64454
• MGIID: 1890478
• Length: 660
• Species: Mus musculus
• Sequence 2: NP_001138069.2
• Gene: CG31262 / 318649
• FlyBaseID: FBgn0051262
• Length: 579
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 137/639 - (21%)
• Similarity: 240/639 - (37%)
• Gaps: 166/639 - (25%)

Mouse    28 DISVIVIYFIVVLAVGLW------------SMVRSNRGT------VGGFFLAGHDMAWWPMGASL 74
            |..|:|...::....|::            |:...||.|      :..:.:...:|...|:..:|
  Fly    10 DYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPVSITL 74

Mouse    75 F--ASNIGS----NHFVGLAGTGAASGIAIAAVEWNALLMVLVLGWVFLPIYIKAGVLTMPEYLR 133
            :  .|.||:    .|:      |....:.|.|:    :|..:...:|:||:|....:.:..|||.
  Fly    75 YRVTSIIGTPSEIYHY------GTQYYLIIVAI----ILQGIAFSYVYLPVYSALQIGSAYEYLG 129

Mouse   134 KRFGGKRLQIYLSVLSLFIMVALQT--SSIIFSGAIFIQLALGLNLYLAVFILLAITAFYTVAGG 196
            .||.    .|..:..|...:..:.|  ..|::..|:.:....|||.:|...:::.....||..||
  Fly   130 LRFN----SIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMGG 190

Mouse   197 LASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAIPSVV----EGDNLTISPKCYT 257
            |.:|::||..|..:|.|.   |:..||..:        .|.|.:.:|.    :|..|.::..  .
  Fly   191 LKAVVHTDVWQVAVMFLS---LVAVAFLAI--------YYSNGLVAVFDDAEQGGRLMLANT--N 242

Mouse   258 PQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYW----CADQVIVQRCLCGKNMSHVKAACI--- 315
            |.|...|..         |..||.|.:     :|    ...|.:|||.:...::...:.|..
  Fly   243 PSPYVRHTV---------WSVLIGGFS-----FWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFT 293

Mouse   316 --------LCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECEKQCGTAVGCTNYAYPTLVLE 372
                    ||.::.||         :.|:  |.|         |:.:....:...:...|..|::
  Fly   294 IGVSIFIALCCFMGLL---------LFSK--YKD---------CDPRSAGMILNDDQLLPLFVVQ 338

Mouse   373 LMPD--GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKIRK-KASERE--LMIAGRIFGMV 432
            .:..  |:.||.::.:..:.:|||:|.||:.|.:|..|:.....| :.|||:  ::|...|....
  Fly   339 SVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQSTILIKTCIIFQG 403

Mouse   433 LIAVSILWVPLVQVSQNGQLFHYIG------SVSSYLGPPLGAVFMLAIFFKRVNEQG-AFWGLM 490
            ::|..|:::          |.|..|      |:||........||.|.:.|...|..| |..||.
  Fly   404 ILAFLIVFL----------LQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLS 458

Mouse   491 VGLVVGLIRLIAEFVYGTG------------SCVAPSNCPK----------IICGVHYMYFAIIL 533
            ..|:.|.|...::....:|            .||.....|:          .:..:.|.:.:.|.
  Fly   459 SVLLAGWISFGSQIAAASGQLKSGMLPVSVKECVGNVTLPEDPWVDQDQVFPLYRLSYHWVSPIG 523

Mouse   534 FFVSIIVILGVSFLTEPI-----------PDVH--LYRLCW---SLWNNTEERI 571
            ...:::|...||.:|:|.           |.:|  |.|.|:   :|...|||.:
  Fly   524 VVTAVVVGALVSLITKPADIKTLHAELISPVIHRFLPRECFRGRNLNERTEESL 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a4b	NP_075708.2	SLC5-6-like_sbd	27..660	CDD:294310	137/639 (21%)
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	122/582 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750