Protein Alignment Slc5a4a and CG33124

DIOPT Version :9

• Sequence 1: NP_573447.2
• Gene: Slc5a4a / 64452
• MGIID: 1927848
• Length: 656
• Species: Mus musculus
• Sequence 2: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 637
• Identity: 140/637 - (21%)
• Similarity: 262/637 - (41%)
• Gaps: 153/637 - (24%)

Mouse    28 DISVIVIYFVVVMAVGV---WAMLKTNR-------------------STVGGFFLAGRSMTWWPM 70
            |.:|.:...::.:|:|:   | :.||.:                   ..:..:.:....:..:|:
  Fly    10 DYTVFLGVTILSIAIGLYFGW-IKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPV 73

Mouse    71 GASLFASNIGSGHFVGLAGTGAASGIAVTAFESHSFALLLVL-----GWIFVPIYIKAGVMTMPE 130
            ..||.||.|.     |:|..|..|.|.....:.....|.:|:     .:|::|::....|.:..|
  Fly    74 AMSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYE 133

Mouse   131 YLKKRFGGKRLQIYLSILFLFICVILTISADIFSGAIFIKLALGLNLYLAILILLAITAIFTITG 195
            ||..|| ...::..:||:|: |.|:|.....:|..|:.:..|.|||:::..::::.:..|:|:.|
  Fly   134 YLGMRF-HPLIRNIVSIMFV-IEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLLG 196

Mouse   196 GLASVIYTDTVQAVIMLVGSFILMVFAFVEVGGYESFTEKFMNAIPSVVEGDNLTINSRCYTPQP 260
            ||.:|::||..|.|||.....::.:.|...:...:.|.|       |:|:|..|
  Fly   197 GLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFE-------SLVDGGRL----------- 243

Mouse   261 DSFHIFRDPVTGDI-PWP---GTAFGMPITALWYW----CINQVIVQRCLCGKNL--SHVKAACI 315
                     :.|:| |.|   .|.:.:.|...:||    .::|.:|.|.:...||  :....|..
  Fly   244 ---------IFGNINPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFF 299

Mouse   316 LCGYLKLLPLFFMVMP--GMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPMLVLKLMP--M 376
            :.|.:    :|:.|:.  |::...:|.|         |.......:...:...|:.|::.:.  .
  Fly   300 VLGSI----IFYSVLSFLGLLIFNMYKD---------CDPLSAGQIMNNDQLVPLFVVQSVGHIY 351

Mouse   377 GLRGLMLSVMLASLMSSLTSVFNSASTLFTIDLY------------TKIRKKASERELLIAGRL- 428
            |:.||.::.:..:.:|||:...||.|.:...|:.            :.|..||:   ::|.|.|
  Fly   352 GIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKAT---IVIMGALV 413

Mouse   429 FVSVLIVTSILWVPIVEVSQGGQLVHYTEAISSYLGPPIAAVFLVAVFCKRANEQGAFWGLMVG- 492
            |..||::..:..:..:.:|    ||  ..|.||..|     :|.:||....||..|...|.:.|
  Fly   414 FGEVLLLEKVSGILSICMS----LV--AIATSSTFG-----IFTLAVLVPWANTVGTAVGGIAGF 467

Mouse   493 LVMGLIRMIAEFSYGTGSC------LAPSSCPKIICGVHYLY---------FAIILFFV-----C 537
            |:.|.|...::.:..:|..      ::.:|||..:.....::         |.:...::     .
  Fly   468 LLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHWINPIGAL 532

Mouse   538 ILVILG--VSYLTKPI-----------PDVH--LHRLCWALRN-SKEERIDL 573
            .:|::|  ||.:|||.           |.:|  |.:.|:..|| .|.|..|:
  Fly   533 TVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDKSEATDI 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc5a4a	NP_573447.2	SLC5-6-like_sbd	27..656	CDD:294310	140/637 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	574..593		140/637 (22%)
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	124/584 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750