Protein Alignment ACTR6 and Act88F

DIOPT Version :10

• Sequence 1: NP_071941.1
• Gene: ACTR6 / 64431
• HGNCID: 24025
• Length: 396
• Species: Homo sapiens
• Sequence 2: NP_524367.1
• Gene: Act88F / 41885
• FlyBaseID: FBgn0000047
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 412
• Identity: 105/412 - (25%)
• Similarity: 190/412 - (46%)
• Gaps: 68/412 - (16%)

Human     4 LVLDNGAYNAKIGYSHENVSVIPNCQFRSKTARLK------------TFTANQIDEIKDPSGLFY 56
            ||:|||:...|.|::.::.   |...|.|...|.:            ::..   ||.:...|:..
  Fly     9 LVIDNGSGMCKAGFAGDDA---PRAVFPSIVGRPRHQGVMVGMGQKDSYVG---DEAQSKRGILT 67

Human    57 I-LPFQKGYLVNWDVQRQVWDYLFGKEMYQVDFLDTNIIITEPYFNFTSIQESMNEILFEEYQ-- 118
            : .|.:.|.:.|||...::|.:.|..|: :|...:..:::||...|..:.:|.|.:|:||.:.
  Fly    68 LKYPIEHGIITNWDDMEKIWHHTFYNEL-RVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSP 131

Human   119 -----FQAVLRVNAGALSAHRYFRDNPSELCCIIVDSGYSFTHIVPYCRSKKKKEAIIRINVGGK 178
                 .||||.:.|...:..            |::|||...:|.||.........||:|:::.|:
  Fly   132 AMYVAIQAVLSLYASGRTTG------------IVLDSGDGVSHTVPIYEGFALPHAILRLDLAGR 184

Human   179 LLTNHLKEIISYR--QLHVMDETHVINQVKEDVCYVSQDFYRDMDIAKLKGEENTVMIDYVLPDF 241
            .||::|.:|::.|  ......|..::..:||.:|||:.||.::|..|   ....::...|.|||
  Fly   185 DLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATA---AASTSLEKSYELPD- 245

Human   242 STIKKGFCKPREEMVLSGKYKSGEQILRLANERFAVPEILFNPSDIGIQEMGIPEAIVYSIQNLP 306
                                   .|::.:.||||..||.||.||.:|::..||.|.:..||....
  Fly   246 -----------------------GQVITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCD 287

Human   307 EEMQPHFFKNIVLTGGNSLFPGFRDRVYSEVRCLTPTDYDVSVVLPENPITYAWEGGKLISENDD 371
            .:::...:.|.||:||.:::||..||:..|:..|.|:...:.::.|.......|.||.:::....
  Fly   288 VDIRKDLYANSVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLST 352

Human   372 FEDMVVTREDYEENGHSVCEEK 393
            |:.|.:::::|:|:|..:...|
  Fly   353 FQQMWISKQEYDESGPGIVHRK 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTR6	NP_071941.1	ASKHA_NBD_Arp6	3..386	CDD:466816	103/403 (26%)
Act88F	NP_524367.1	ASKHA_NBD_actin	8..371	CDD:466823	104/407 (26%)