DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HHIP and CG3513

DIOPT Version :9

Sequence 1:NP_071920.1 Gene:HHIP / 64399 HGNCID:14866 Length:700 Species:Homo sapiens
Sequence 2:NP_608798.1 Gene:CG3513 / 33590 FlyBaseID:FBgn0031559 Length:88 Species:Drosophila melanogaster


Alignment Length:115 Identity:22/115 - (19%)
Similarity:33/115 - (28%) Gaps:53/115 - (46%)


- Green bases have known domain annotations that are detailed below.


Human   552 LGFGEDELGEVYILSSSKSMTQTHNGKLYKIVDPKRPLMPEECRATVQPAQTLTSECSRLCRNGY 616
            :||    :...::||.|.|....|             ..||.|:   ||:..:.           
  Fly     4 IGF----VAIAFLLSLSGSRLWVH-------------AKPEMCQ---QPSSMVG----------- 37

Human   617 CTPTGKCCCS--PGWEGD--------------------FCRTAKCEPACR 644
            ....|..|.:  |.|..|                    |...::||.||:
  Fly    38 MAQDGAACMAFMPAWTYDASKNACTEFIFGGCGGNSNQFSTKSECEKACK 87

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HHIPNP_071920.1 Folate_rec 38..220 CDD:281076
GSDH 226..>428 CDD:285269
Interaction with SHH zinc binding site 376..388
CG3513NP_608798.1 KU 29..87 CDD:238057 12/71 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4295
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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