DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Calu and CG31650

DIOPT Version :9

Sequence 1:	NP_001029070.1	Gene:	Calu / 64366	RGDID:	620383	Length:	315	Species:	Rattus norvegicus
Sequence 2:	NP_001162879.1	Gene:	CG31650 / 326150	FlyBaseID:	FBgn0031673	Length:	342	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	123/347 - (35%)
Similarity:	190/347 - (54%)	Gaps:	51/347 - (14%)

- Green bases have known domain annotations that are detailed below.

  Rat     7 LMCLSLCT--------------AFALSKPTEK---KDRV----------HHEPQLSDKVHNDAQN 44
            |:.|:||.              |.|.|...||   |:||          ||..:  |..|    |
  Fly     7 LLPLTLCAVALLAAVGPMPAHGAVANSHKHEKHLSKERVKDGIYAPRDAHHHGE--DGEH----N 65

  Rat    45 FDYDHDAFLG-AEEAKSFDQLTPEESKERLGMIVDKIDTDKDGFVTKGELKSWIKHAQKKYIYDN 108
            .::||:|.:| .:||:.||.|:|:|||.||.:::..:|.:||.|:.:.|||:||..:.||...:.
  Fly    66 VEFDHEAIIGNTKEAQEFDSLSPDESKRRLLILIKMMDLNKDEFIDRHELKAWILRSFKKLSEEE 130

  Rat   109 VENQWQEFDMNQDGLISWDEYRNVTYGTYLDDPD------PDDGFNYKQMMVR-DERRFKMADKD 166
            ..::::|.|.:.|..|:|.||...||.  ::|.|      ..|.:..:|.|:: |:..|..||.:
  Fly   131 AADRFEEIDQDADERITWKEYLQDTYA--MEDEDFKKETIDYDSYEDEQKMIKQDKEMFNAADTN 193

  Rat   167 GDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNADEPEWVK 231
            .|.:.|.|||..|.:|||:..|..|:::.||:|.|.:.||.|:.:|::||..||    .:.||:.
  Fly   194 KDGVLTLEEFVLFQNPEEHPQMLPILLEHTMQDKDADHDGKINFQEFVGDAASH----HDKEWLI 254

  Rat   232 TEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQDKDGKLTKEEIVDKYDL 296
            ||:|:|.:..|.|.||.:..:|...||:||:...|..|..||...:|:|.|.:|:..||::.||.
  Fly   255 TEKERFDKDHDSNGDGVLTGDEVLSWIVPSNTAIANDEVDHLFVSTDEDHDDRLSYLEILNNYDT 319

  Rat   297 FVGSQATDFGEAL--VRH--DE 314
            ||||:|||:|:.|  :.|  ||
  Fly   320 FVGSEATDYGDHLQNINHLSDE 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Calu	NP_001029070.1	EFh	45..98	CDD:298682	23/53 (43%)
		EF-hand_7	73..129	CDD:290234	17/55 (31%)
		EF-hand_7	157..214	CDD:290234	22/56 (39%)
		EFh	157..214	CDD:238008	22/56 (39%)
		EFh	193..258	CDD:298682	23/64 (36%)
CG31650	NP_001162879.1	EF-hand_7	100..153	CDD:290234	18/52 (35%)
		EFh	100..153	CDD:298682	18/52 (35%)
		EF-hand_7	184..241	CDD:290234	22/56 (39%)
		EFh	184..241	CDD:298682	22/56 (39%)
		EFh	228..281	CDD:298682	20/56 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I11881
eggNOG	1	0.900	-	-		E1_KOG4223
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D372250at33208
OrthoFinder	1	1.000	-	-		FOG0000638
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820