Protein Alignment LIPK and Lip2

DIOPT Version :10

• Sequence 1: XP_011538375.1
• Gene: LIPK / 643414
• HGNCID: 23444
• Length: 419
• Species: Homo sapiens
• Sequence 2: NP_524667.1
• Gene: Lip2 / 43980
• FlyBaseID: FBgn0024740
• Length: 413
• Species: Drosophila melanogaster
• Alignment Length: 421
• Identity: 117/421 - (27%)
• Similarity: 189/421 - (44%)
• Gaps: 85/421 - (20%)

Human    44 GNNAN---PEAN-----------MNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRT 94
            |.||:   ||:.           .|:|         :|.::|||.|||.|.:.|:|       |.
  Fly    20 GRNAHSSPPESRYKWTTMDWLEAQNVS---------HEVHNVTTADGYQLQLQRLP-------RL 68

Human    95 APKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRG-NTWSRKHLKLSPKSPEYW 158
            ..|| |.|.|||:.|:..|:|..|..||||.|....|||||.|.|| :.:.|:|:.|:....|:|
  Fly    69 GAKP-VLLVHGLLGSSLGWVCMGPERSLAFQLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFW 132

Human   159 AFSLDEMAKYDLPATINFIIEKTGQKRL-----------------YYVGHSQGTTIAFIAFSTNP 206
            .||..|...|||||.|:.:.:.||.::|                 ..:||||......:..:.:|
  Fly   133 RFSFHEHGAYDLPAIIDHMAKVTGGEQLASRGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHP 197

Human   207 ELAKKIKIFFALAPVV----TVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQFIATKVCN 267
            ...::|::..||||:.    .|::....:       ||::|.:...:..:...:|......|||.
  Fly   198 RFNQRIQLIQALAPLARLHRQVRFDSFQV-------RRLMKFIKKRQKAYKFEIFPPGYFRKVCQ 255

Human   268 RKLFRRICSNFLFTLSGFDPQNLNMSRLDVY-LSHNPAGTSVQNMLHWAQAVNSGQLQAFDWGNS 331
            .|  |.:|..:...|.| ..|| |...|:.: ..:...|.|.:.:.|..|...||...::|:|.:
  Fly   256 AK--RDLCEYYAKQLVG-SAQN-NKKLLEAFNYEYLLQGGSPREIKHLQQIWKSGDFISYDFGTA 316

Human   332 DQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIANLIYYKLI--------- 387
             :|:..:|.:....|||:::.||..::.|..|.:|.|:.|        :.||.:::
  Fly   317 -ENLQVYHSVEALSYNISQITVPIILYFGETDAIATPEGV--------HAIYARMLRSVKSVRRI 372

Human   388 --PHYNHVDFYLGEDAPQEIYQDLIILMEEY 416
              ..:||:||.:..|....:...||..||::
  Fly   373 NSKKFNHLDFLISGDVKSLVNDKLIEHMEQF 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LIPK	XP_011538375.1	PLN02872	31..410	CDD:215470	113/413 (27%)
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	114/417 (27%)